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Found 40 with Last Name = 'kasten' and Initial = 'tp'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113299(5-[3-Nitro-4-(6-nitro-benzothiazol-2-ylsulfanyl)-b...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113293(4-[4-Oxo-5-(3-phenyl-allylidene)-2-thioxo-thiazoli...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113297(3-(4,5-Bis-biphenyl-4-yl-1H-imidazol-2-yl)-phenol ...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113296(2-Hydroxy-4-[5-(4-oxo-3-phenyl-2-phenylimino-thiaz...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113295(1-[5-(4-Chloro-phenyl)-2-phenyl-2H-pyrazol-3-yl]-3...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113303(2-Chloro-4-{5-[1-(3-chloro-phenyl)-3-methyl-5-oxo-...)
Affinity DataIC50:  1.93E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113302(CHEMBL420925 | N-[1-(4-Hydroxy-phenylcarbamoyl)-2-...)
Affinity DataIC50:  2.15E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113301(4-(3-Benzyl-4-oxo-2-thioxo-thiazolidin-5-ylideneme...)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269532((6,9,12)-linolenic acid | (6Z,9Z,12Z)-octadeca-6,9...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50240347((9,12,15)-linolenic acid | (9Z,12Z,15Z)-octadeca-9...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50242188(6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pent...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269540(6-(8'Z,11'Z-heptadecadienyl)-salicylicacid | CHEMB...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113294(2-[2-(5-Bromo-furan-2-carbonyloxy)-acetylamino]-be...)
Affinity DataIC50:  3.44E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113300(Acetic acid 4-(2-benzo[1,3]dioxol-5-yl-5-oxo-oxazo...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM22231((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269533(CHEMBL464983 | cis-11,14-eicosadienoicacid)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113298(3,4-Dichloro-N-[4-(4-chloro-benzenesulfonyl)-5-met...)
Affinity DataIC50:  6.39E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269530((9Z)-tetradec-9-enoic acid | CHEMBL456732 | cis-De...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50259930(6-(10'Z-heptadecenyl)-salicylicacid | 6-[10'(Z)-he...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269534((8Z,11Z,14Z)-Icosatrienoic acid | (8Z,11Z,14Z)-ico...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269534((8Z,11Z,14Z)-Icosatrienoic acid | (8Z,11Z,14Z)-ico...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50242349((5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic ...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50150484((Z)-9-octadecenoic acid | (Z)-Octadec-9-enoic acid...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269535((11Z,14Z,17Z)-Eicosa-11,14,17-trienoic acid | (11Z...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM22319((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269531((9Z)-hexadec-9-enoic acid | (Z)-9-hexadecenoic aci...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269530((9Z)-tetradec-9-enoic acid | CHEMBL456732 | cis-De...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50150484((Z)-9-octadecenoic acid | (Z)-Octadec-9-enoic acid...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM22231((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50240347((9,12,15)-linolenic acid | (9Z,12Z,15Z)-octadeca-9...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269532((6,9,12)-linolenic acid | (6Z,9Z,12Z)-octadeca-6,9...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269533(CHEMBL464983 | cis-11,14-eicosadienoicacid)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269535((11Z,14Z,17Z)-Eicosa-11,14,17-trienoic acid | (11Z...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM22319((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50242349((5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic ...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50242188(6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pent...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50259930(6-(10'Z-heptadecenyl)-salicylicacid | 6-[10'(Z)-he...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269540(6-(8'Z,11'Z-heptadecadienyl)-salicylicacid | CHEMB...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269531((9Z)-hexadec-9-enoic acid | (Z)-9-hexadecenoic aci...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50269534((8Z,11Z,14Z)-Icosatrienoic acid | (8Z,11Z,14Z)-ico...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed