Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
Affinity DataIC50: 16.8nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
Affinity DataIC50: 21.2nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 21.7nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 28.7nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair