TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 154nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Molecular Insight Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 277nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair