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Found 2425 with Last Name = 'kelly' and Initial = 'j'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329148(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305990(CHEMBL596388 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329147(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329151(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305989(CHEMBL596387 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373621(CHEMBL403414)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329150(1,1,1-trifluoro-N-(1-(1-(1-(2-fluorophenylsulfonyl...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329130((S)-1,1,1-trifluoro-N-(6-(1-(pyridin-2-ylsulfonyl)...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329129(CHEMBL1271093 | N-((4-ethyl-1-(5-fluoro-1-(2-fluor...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329144(1,1,1-trifluoro-N-(((3S,4R)-1-(1-(2-fluorophenylsu...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306002(CHEMBL595705 | N-(6-(5-chloro-2-(4-methoxyphenylsu...)
Affinity DataKi:  0.650nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329159((R)-N-(1-(4-(4-chloro-2-(2-fluorophenylsulfonyl)ph...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211605((S)-N-(1-(4-(4-chloro-2-(2-fluorophenylsulfonyl)ph...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373623(CHEMBL404461)
Affinity DataKi:  0.75nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329137(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329133(1,1,1-trifluoro-N-((1-(1-(pyridin-2-ylsulfonyl)-1H...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306008(1,1,1-trifluoro-N-(6-(2-(pyridin-2-ylsulfonyl)-5-(...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329139((S)-1,1,1-trifluoro-N-(6-(1-(2-fluorophenylsulfony...)
Affinity DataKi:  1nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373639(CHEMBL428423)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373624(CHEMBL255353)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329135(1,1,1-trifluoro-N-((1-(2-(2-fluorophenylsulfonyl)f...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373625(CHEMBL403918)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306017(CHEMBL604704 | N-((1R,5S,6s)-3-(4-chloro-2-(2-fluo...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329143(1,1,1-trifluoro-N-(((3S,4S)-1-(1-(2-fluorophenylsu...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329128(1,1,1-trifluoro-N-((4-propyl-1-(1-(pyridin-2-ylsul...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306007(CHEMBL592896 | N-(6-(5-chloro-2-(pyridin-2-ylsulfo...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306016(CHEMBL596579 | N-(6-(4-chloro-2-(2-fluorophenylsul...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373626(CHEMBL257940)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329146(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373622(CHEMBL255147)
Affinity DataKi:  2nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306003(1,1,1-trifluoro-N-(6-(2-(2-fluorophenylsulfonyl)-5...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373622(CHEMBL255147)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329127(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373649(CHEMBL257022)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373655(CHEMBL257707)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305993(CHEMBL594300 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306005(1,1,1-trifluoro-N-(6-(2-(2-fluorophenylsulfonyl)-5...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329140(CHEMBL1270287 | N-(((3S,4S)-4-ethyl-1-(1-(2-fluoro...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373653(CHEMBL429679)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373656(CHEMBL428953)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373654(CHEMBL257708)
Affinity DataKi:  3.40nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329141(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329156((R)-1,1,1-trifluoro-N-(1-(4-(2-(2-fluorophenylsulf...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306004(1,1,1-trifluoro-N-(6-(2-(pyridin-2-ylsulfonyl)-5-(...)
Affinity DataKi:  5nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305994(CHEMBL593595 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305991(CHEMBL595481 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306006(CHEMBL603321 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373650(CHEMBL257248)
Affinity DataKi:  5.90nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373651(CHEMBL257457)
Affinity DataKi:  6.30nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306018(CHEMBL595460 | N-(((3R,4S)-1-(4-chloro-2-(2-fluoro...)
Affinity DataKi:  7nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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