TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Oncobix
US Patent
Oncobix
US Patent
Affinity DataIC50: 0.0800nMAssay Description:The inhibitory activity on a C797S-containing epidermal growth factor receptor (EGFR) kinase and an MET kinase was measured for compound 1 obtained i...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:The inhibitory activity on a C797S-containing epidermal growth factor receptor (EGFR) kinase and an MET kinase was measured for compound 1 obtained i...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The inhibitory activity on a C797S-containing epidermal growth factor receptor (EGFR) kinase and an MET kinase was measured for compound 1 obtained i...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Oncobix
US Patent
Oncobix
US Patent
Affinity DataIC50: 2nMAssay Description:The inhibitory activity on a C797S-containing epidermal growth factor receptor (EGFR) kinase and an MET kinase was measured for compound 1 obtained i...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Oncobix
US Patent
Oncobix
US Patent
Affinity DataIC50: 6nMAssay Description:The inhibitory activity on a C797S-containing epidermal growth factor receptor (EGFR) kinase and an MET kinase was measured for compound 1 obtained i...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:The inhibitory activity on a C797S-containing epidermal growth factor receptor (EGFR) kinase and an MET kinase was measured for compound 1 obtained i...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:The inhibitory activity on a C797S-containing epidermal growth factor receptor (EGFR) kinase and an MET kinase was measured for compound 1 obtained i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Compound was tested for selectivity against human T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 2.40E+5nMAssay Description:Compound was tested for selectivity against human T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 3.10E+5nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 4.60E+5nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+5nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: 7.80E+5nMAssay Description:Compound was tested for selectivity against human T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Compound was tested for selectivity against LARMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair