BindingDB PrimarySearch_ki

Found 1045 with Last Name = 'kim' and Initial = 'nd'

Cyclin-Y(Homo sapiens)
Harvard Medical School

Curated by ChEMBL

PNG

BDBM50535590(CHEMBL4563703)

IC50: 0.400nMAssay Description:Inhibition of recombinant GST-tagged human full length CDK14/cyclin Y (2 to end residues) preincubated for 30 mins by Lantha screen eu binding assayMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Details Article PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL

PNG

BDBM50193013(Duvelisib | INK-1147 | INK-1197 | IPI-145)

IC50: <0.5nMAssay Description:Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596833(CHEMBL5193966)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596833(CHEMBL5193966)

IC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596832(CHEMBL5198569)

IC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596831(CHEMBL5177100)

IC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596830(CHEMBL5179166)

IC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)

IC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596852(CHEMBL5193739)

IC50: <0.5nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596833(CHEMBL5193966)

IC50: <0.5nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596833(CHEMBL5193966)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596834(CHEMBL5181852)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596834(CHEMBL5181852)

IC50: <0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596832(CHEMBL5198569)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596831(CHEMBL5177100)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Focal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL

PNG

BDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)

IC50: <0.5nMAssay Description:Inhibition of recombinant FAK (unknown origin) by radiometric kinase assayMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596830(CHEMBL5179166)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596831(CHEMBL5177100)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596832(CHEMBL5198569)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596833(CHEMBL5193966)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Fibroblast growth factor receptor 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596834(CHEMBL5181852)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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3D Structure (crystal)

Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596830(CHEMBL5179166)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50525939(Balversa | Erdafitinib | Jnj-42756493)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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3D Structure (crystal)

Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)

IC50: <0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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3D Structure (crystal)

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: <0.510nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596831(CHEMBL5177100)

IC50: 0.520nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596832(CHEMBL5198569)

IC50: 0.580nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596831(CHEMBL5177100)

IC50: 0.600nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596832(CHEMBL5198569)

IC50: 0.600nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)

IC50: 0.660nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)

IC50: 0.680nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50413752(CHEMBL2012519 | L-783277)

IC50: 0.730nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

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Cyclin-Y(Homo sapiens)
Harvard Medical School

Curated by ChEMBL

PNG

BDBM50535569(CHEMBL4535078)

IC50: 0.800nMAssay Description:Inhibition of recombinant GST-tagged human full length CDK14/cyclin Y (2 to end residues) preincubated for 30 mins by Lantha screen eu binding assayMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Details Article PubMed

Fibroblast growth factor receptor 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596830(CHEMBL5179166)

IC50: 0.920nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Bone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50262079(4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...)

IC50: 0.940nMAssay Description:Inhibition of human ALK6 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair

PDB
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3D Structure (crystal)

Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM301310(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...)

IC50: 0.970nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596834(CHEMBL5181852)

IC50: 0.980nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Cyclin-Y(Homo sapiens)
Harvard Medical School

Curated by ChEMBL

PNG

BDBM50535532(CHEMBL4534124)

IC50: <1nMAssay Description:Inhibition of recombinant GST-tagged human full length CDK14/cyclin Y (2 to end residues) preincubated for 30 mins by Lantha screen eu binding assayMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Details Article PubMed

Serine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent

PNG

BDBM50038473(CHEMBL3354844 | US9216981, 18)

IC50: 1nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Cyclin-Y(Homo sapiens)
Harvard Medical School

Curated by ChEMBL

PNG

BDBM50535520(CHEMBL4560035)

IC50: <1nMAssay Description:Inhibition of recombinant GST-tagged human full length CDK14/cyclin Y (2 to end residues) preincubated for 30 mins by Lantha screen eu binding assayMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Details Article PubMed

Mitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50459208(CHEMBL4214342)

IC50: 1nMAssay Description:Inhibition of GCK (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

MMDB Reactome pathway KEGG
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Serine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent

PNG

BDBM197687(US9216981, 15)

IC50: 1nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Cyclin-Y(Homo sapiens)
Harvard Medical School

Curated by ChEMBL

PNG

BDBM50535547(CHEMBL4522564)

IC50: <1nMAssay Description:Inhibition of recombinant GST-tagged human full length CDK14/cyclin Y (2 to end residues) preincubated for 30 mins by Lantha screen eu binding assayMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

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Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50413752(CHEMBL2012519 | L-783277)

IC50: 1.10nMAssay Description:Inhibition of human FLT4 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50509140(CHEMBL4453304)

IC50: 1.10nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50509146(CHEMBL4303275)

IC50: 1.20nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596850(CHEMBL5200941)

IC50: 1.20nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

PNG

BDBM50596851(CHEMBL5204120)

IC50: 1.40nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Displayed 1 to 50 (of 1045 total ) | Next | Last >>

Filter my 1045 hits

Targets 77▿
- Cyclin-Y 92
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 88
- Serine/threonine-protein kinase B-raf 88
- Proto-oncogene tyrosine-protein kinase receptor Ret 73
- Fibroblast growth factor receptor 3 59
- Focal adhesion kinase 1 43
- Calpain-1 catalytic subunit 39
- Estrogen-related receptor gamma 36
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 34
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 34
- Fibroblast growth factor receptor 2 33
- Mitogen-activated protein kinase kinase kinase kinase 2 30
- Activated CDC42 kinase 1 30
- Bifunctional epoxide hydrolase 2 22
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 20
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 20
- Aurora kinase B 18
- Fibroblast growth factor receptor 1 18
- Aurora kinase A 18
- Vascular endothelial growth factor receptor 2 17
- Vascular endothelial growth factor receptor 3 17
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 16
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 16
- Receptor-type tyrosine-protein kinase FLT3 13
- Cyclin-dependent kinase 14 13
- Serine/threonine-protein kinase PLK1 12
- Fibroblast growth factor receptor 4 9
- Estrogen receptor 8
- Serine/threonine-protein kinase receptor R3 8
- Steroid hormone receptor ERR1 8
- Steroid hormone receptor ERR2 8
- Interleukin-10 7
- Heat shock protein HSP 90-alpha/90-beta 7
- Serine/threonine-protein kinase SIK2 7
- Bromodomain-containing protein 4 5
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 4
- Dual specificity protein kinase TTK 4
- Cytochrome P450 1A2 4
- Cytochrome P450 2C9 4
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 4
- Cytochrome P450 2C19 4
- Cytochrome P450 2D6 4
- Cytochrome P450 3A4 4
- Dual specificity mitogen-activated protein kinase kinase 2 3
- Activin receptor type-1 3
- Aurora kinase C 3
- TGF-beta receptor type-1 2
- Serine/threonine-protein kinase PLK4 2
- Dual specificity mitogen-activated protein kinase kinase 6 2
- Leucine-rich repeat serine/threonine-protein kinase 2 2
- Bone morphogenetic protein receptor type-1B 2
- Bone morphogenetic protein receptor type-1A 2
- Activin receptor type-1B 2
- Tyrosine-protein kinase Lck 1
- Interleukin-1 receptor-associated kinase 1 1
- Proto-oncogene tyrosine-protein kinase ROS 1
- Tyrosine-protein kinase Fyn 1
- Tyrosine-protein kinase JAK1 1
- Serine/threonine-protein kinase 16 1
- Cyclin-dependent kinase 4 1
- Potassium voltage-gated channel subfamily H member 2 1
- Platelet-derived growth factor receptor alpha 1
- Cyclin-Y/Cyclin-dependent kinase 2 1
- Tyrosine-protein kinase JAK3 1
- Ephrin type-B receptor 1 1
- Dual specificity mitogen-activated protein kinase kinase 1 1
- Ribosomal protein S6 kinase alpha-1 1
- ALK tyrosine kinase receptor 1
- Ribosomal protein S6 kinase beta-1 1
- Proto-oncogene tyrosine-protein kinase Src 1
- Epithelial discoidin domain-containing receptor 1 1
- Non-receptor tyrosine-protein kinase TYK2 1
- Tyrosine-protein kinase Fes/Fps 1
- Tyrosine-protein kinase Fgr 1
- Casein kinase II subunit alpha 1
- Tyrosine-protein kinase HCK 1
- Vascular endothelial growth factor receptor 1 1
- ...
Publications 23▿
- J Med Chem 62: 8461-8479 (2019) 122
- J Med Chem 65: 6017-6038 (2022) 121
- Bioorg Med Chem Lett 29: 1985-1993 (2019) 106
- US Patent US9216981 (2015) 88
- ACS Med Chem Lett 7: 908-912 (2016) 75
- J Med Chem 59: 358-73 (2016) 68
- J Med Chem 61: 8353-8373 (2018) 60
- Eur J Med Chem 120: 338-52 (2016) 60
- J Med Chem 64: 11934-11957 (2021) 57
- J Med Chem 62: 9141-9160 (2019) 41
- US Patent US11117892 (2021) 40
- Bioorg Med Chem Lett 19: 2324-8 (2009) 36
- J Med Chem 60: 1495-1508 (2017) 29
- Bioorg Med Chem Lett 19: 502-7 (2008) 25
- Eur J Med Chem 117: 113-24 (2016) 22
- Bioorg Med Chem Lett 27: 4405-4408 (2017) 21
- Eur J Med Chem 125: 1145-1155 (2017) 17
- ACS Chem Biol 11: 2105-11 (2016) 14
- Bioorg Med Chem Lett 18: 205-9 (2008) 14
- J Med Chem 65: 1915-1932 (2022) 12
- Bioorg Med Chem Lett 16: 3772-6 (2006) 12
- J Med Chem 64: 6985-6995 (2021) 4
- ACS Med Chem Lett 2: 379-384 (2011) 1
Institutions 15▿
- Korea University 385
- Harvard Medical School 127
- Medpacto 88
- Korea Institute Of Science And Technology (Kist) 85
- Dana-Farber Cancer Institute 75
- Daegu-Gyeongbuk Medical Innovation Foundation 60
- Yonsei University College Of Medicine 57
- TBA 41
- Inje University 36
- Shenyang Pharmaceutical University 25
- Chungnam National University 22
- Kyung Hee University 14
- Broad Institute 14
- Research Center Idrtech 12
- Yonsei University 4
Affinity: 0.40 to 5.0E+4 nM▿
- IC50 988
- EC50 57
- Affinity ≤ nM
Xtal structures: 15
Docked structures: 2
Catalog Cmpds: 47