Affinity DataKi: 0.290nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.660nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 9.60nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair