BindingDB PrimarySearch

Found 301 with Last Name = 'klumpp' and Initial = 'c'

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567821(CHEMBL4875277)

IC50: 35nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567821(CHEMBL4875277)

IC50: 39nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567816(CHEMBL4851708)

IC50: 39nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567825(CHEMBL4861426)

IC50: 42nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567833(CHEMBL4868649)

IC50: 44nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567808(CHEMBL4860083)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567832(CHEMBL4878489)

PDB Reactome pathway KEGG
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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567815(CHEMBL4864243)

PDB Reactome pathway KEGG
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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567815(CHEMBL4864243)

IC50: 46nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567828(CHEMBL4854924)

IC50: 47nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567819(CHEMBL4845768)

IC50: 48nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567809(CHEMBL4848154)

IC50: 49nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567820(CHEMBL4858156)

IC50: 49nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567816(CHEMBL4851708)

IC50: 53nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567824(CHEMBL4879014)

IC50: 55nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Details Article PubMed

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567809(CHEMBL4848154)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567832(CHEMBL4878489)

IC50: 55nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567823(CHEMBL4872718)

IC50: 56nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567830(CHEMBL4878829)

IC50: 56nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567808(CHEMBL4860083)

IC50: 58nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Details Article PubMed

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567827(CHEMBL4873139)

IC50: 60nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567820(CHEMBL4858156)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567828(CHEMBL4854924)

IC50: 62nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM363689(US10640534, Compound 176 | US10682352, Compound AG...)

IC50: 63nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase MCE
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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567782(CHEMBL4857251)

IC50: 64nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567826(CHEMBL4872262)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567824(CHEMBL4879014)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM363689(US10640534, Compound 176 | US10682352, Compound AG...)

IC50: 65nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase MCE
PC cid PC sid

Details Article PubMed

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50503248(CHEMBL4448475)

IC50: 72nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567817(CHEMBL4853810)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567812(CHEMBL4864581)

IC50: 75nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567834(CHEMBL4851468)

IC50: 75nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567834(CHEMBL4851468)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567805(CHEMBL4867078)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567819(CHEMBL4845768)

IC50: 78nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50503248(CHEMBL4448475)

IC50: 81nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567818(CHEMBL4863979)

IC50: 82nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567825(CHEMBL4861426)

IC50: 94nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567827(CHEMBL4873139)

PDB Reactome pathway KEGG
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B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567817(CHEMBL4853810)

IC50: 100nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50503248(CHEMBL4448475)

IC50: 100nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567805(CHEMBL4867078)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50503248(CHEMBL4448475)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567833(CHEMBL4868649)

IC50: 110nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567807(CHEMBL4864789)

IC50: 110nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567834(CHEMBL4851468)

IC50: 114nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50503248(CHEMBL4448475)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50503248(CHEMBL4448475)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567834(CHEMBL4851468)

IC50: 120nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins by diaph...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Details Article PubMed

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL

BDBM50567834(CHEMBL4851468)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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