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Found 551 with Last Name = 'krause' and Initial = 'c'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610391(CHEMBL5290966)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610453(2-Phenyl-N-(4-(2,2,2-trifluoroethoxy)pyridin-3-yl)...)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610384(CHEMBL5268011)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613245(CHEMBL5266553)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610396(CHEMBL5278104)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610428(CHEMBL5284020)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613418(CHEMBL5268185)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610483(2-Cyclopropyl-N-(4-(4,4-difluoropiperidin-1-yl)pyr...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610389(CHEMBL5282887)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610462(N-(4-Morpholinopyridin-3-yl)-2-phenylimidazo[1,2-b...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610461(N-(4-(4,4-Difluoropiperidin-1-yl)pyridin-3-yl)-2-p...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610477(N-(4-Morpholinopyridin-3-yl)-2-(4-(trifluoromethyl...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610458(2-Phenyl-N-(4-(piperidin-1-yl)pyridin-3-yl)imidazo...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610383(CHEMBL5283410)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613417(CHEMBL5290300)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50074676(CHEMBL3410091)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of GSK3beta (unknown origin) activity by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610469((S)—N-(4-(3-Methylmorpholino)pyridin-3-yl)-2-pheny...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613415(CHEMBL5273872)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613246(CHEMBL5316226)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50074675(CHEMBL3410092)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of GSK3beta (unknown origin) activity by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610427(CHEMBL5291181)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610476(2-(2-Methoxyphenyl)-N-(4-(2-methylmorpholino)pyrid...)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610454(N-(4-(Methylsulfonyl)pyridin-3-yl)-2-phenylimidazo...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetMicrotubule-associated protein tau(Homo sapiens (Human))TBA
LigandPNGBDBM50610396(CHEMBL5278104)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of tau phosphorylation (unknown origin)More data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610452(N-(4-Isopropoxypyridin-3-yl)-2-phenylimidazo[1,2-b...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610482(2-Cyclopropyl-N-(4-(4-fluorophenyl)pyridin-3-yl)im...)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50074677(CHEMBL3410090)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of GSK3beta (unknown origin) activity by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613407(CHEMBL5269649)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610435(CHEMBL5286043)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610390(CHEMBL5282113)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610478(N-(4-(2-Methylmorpholino)pyridin-3-yl)-2-(4-(trifl...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610431(CHEMBL5276076)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613413(CHEMBL5265990)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610417(CHEMBL5271077)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613402(CHEMBL5270885)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610395(CHEMBL5272041)
Affinity DataIC50:  0.790nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610484(2-Cyclopropyl-N-(4-(2-methylmorpholino)pyridin-3-y...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610451(N-(4-Methylpyridin-3-yl)-2-phenylimidazo[1,2-b]pyr...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50074576(CHEMBL3410111)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of GSK3beta (unknown origin) activity by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610382(CHEMBL5290181)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50613418(CHEMBL5268185)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613414(CHEMBL5280241)
Affinity DataIC50:  0.880nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610385(CHEMBL5273034)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610393(CHEMBL5281590)
Affinity DataIC50:  0.990nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610388(CHEMBL5288950)
Affinity DataIC50:  0.990nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

LigandPNGBDBM29466(Pyrazolo[1,5-a]-1,3,5-triazine, 12-35)
Affinity DataIC50:  1nMT: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610468((R)—N-(4-(3-Methylmorpholino)pyridin-3-yl)-2-pheny...)
Affinity DataIC50:  1nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610398(CHEMBL5273531)
Affinity DataIC50:  1nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610387(CHEMBL5289779)
Affinity DataIC50:  1nMAssay Description:Inhibition of GSK-3beta (unknown origin) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
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