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Found 97 with Last Name = 'krawiec' and Initial = 'ja'
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to PXR by scintillation proximity binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300577((R)-2-(3-(4-((2-chloro-3-(trifluoromethyl)benzyl)(...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to PXR by scintillation proximity binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300575((R)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to PXR by scintillation proximity binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254432(1-(2-methyl-5-(morpholinosulfonyl)furan-3-yl)-3-ph...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254434(5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254343((S)-1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254436(5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254290(1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254290(1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254339(1-(4-methoxyphenyl)-3-(2-methyl-5-(piperidin-1-yls...)
Affinity DataIC50:  130nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254341(1-(2-chlorophenyl)-3-(2-methyl-5-(piperidin-1-ylsu...)
Affinity DataIC50:  130nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254432(1-(2-methyl-5-(morpholinosulfonyl)furan-3-yl)-3-ph...)
Affinity DataIC50:  130nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254339(1-(4-methoxyphenyl)-3-(2-methyl-5-(piperidin-1-yls...)
Affinity DataIC50:  130nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254340(1-(4-chlorophenyl)-3-(2-methyl-5-(piperidin-1-ylsu...)
Affinity DataIC50:  130nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254393(1-benzhydryl-3-(2-methyl-5-(piperidin-1-ylsulfonyl...)
Affinity DataIC50:  160nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254340(1-(4-chlorophenyl)-3-(2-methyl-5-(piperidin-1-ylsu...)
Affinity DataIC50:  200nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254434(5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...)
Affinity DataIC50:  250nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254436(5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...)
Affinity DataIC50:  300nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254341(1-(2-chlorophenyl)-3-(2-methyl-5-(piperidin-1-ylsu...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254435(5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254343((S)-1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254433(1-(2-methyl-5-(4-methylpiperazin-1-ylsulfonyl)fura...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254435(5-Methyl-4-(3-phenyl-ureido)-furan-2-sulfonic acid...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254433(1-(2-methyl-5-(4-methylpiperazin-1-ylsulfonyl)fura...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253974(1-phenyl-3-(5-(piperidin-1-ylsulfonyl)furan-3-yl)u...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254393(1-benzhydryl-3-(2-methyl-5-(piperidin-1-ylsulfonyl...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253974(1-phenyl-3-(5-(piperidin-1-ylsulfonyl)furan-3-yl)u...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254396(1-methyl-1-(2-methyl-5-(piperidin-1-ylsulfonyl)fur...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254396(1-methyl-1-(2-methyl-5-(piperidin-1-ylsulfonyl)fur...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254043(1-(2-methyl-6-(piperidin-1-ylsulfonyl)pyridin-3-yl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253986(1-(2-methyl-4-(morpholinosulfonyl)phenyl)-3-phenyl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253977(1-(1-methyl-3-(piperidin-1-ylsulfonyl)-1H-pyrazol-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253976(1-(1,2-dimethyl-5-(piperidin-1-ylsulfonyl)-1H-pyrr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253975(1-(2-methyl-5-(piperidin-1-ylsulfonyl)-1H-pyrrol-3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253973(1-(2,4-dimethyl-5-(piperidin-1-ylsulfonyl)furan-3-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254397(2-methyl-N-phenyl-5-(piperidin-1-ylsulfonyl)furan-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254395(1-(4-chlorophenyl)-1-methyl-3-(2-methyl-5-(piperid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254394(1-methyl-3-(2-methyl-5-(piperidin-1-ylsulfonyl)fur...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254342(1-benzyl-3-(2-methyl-5-(piperidin-1-ylsulfonyl)fur...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254043(1-(2-methyl-6-(piperidin-1-ylsulfonyl)pyridin-3-yl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253986(1-(2-methyl-4-(morpholinosulfonyl)phenyl)-3-phenyl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253977(1-(1-methyl-3-(piperidin-1-ylsulfonyl)-1H-pyrazol-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253976(1-(1,2-dimethyl-5-(piperidin-1-ylsulfonyl)-1H-pyrr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253975(1-(2-methyl-5-(piperidin-1-ylsulfonyl)-1H-pyrrol-3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50253973(1-(2,4-dimethyl-5-(piperidin-1-ylsulfonyl)furan-3-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254397(2-methyl-N-phenyl-5-(piperidin-1-ylsulfonyl)furan-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254395(1-(4-chlorophenyl)-1-methyl-3-(2-methyl-5-(piperid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254394(1-methyl-3-(2-methyl-5-(piperidin-1-ylsulfonyl)fur...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254342(1-benzyl-3-(2-methyl-5-(piperidin-1-ylsulfonyl)fur...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  80nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
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