Affinity DataKi: 0.150nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]paraxetine from human 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]citalopram form human SRET by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor short form expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]paraxetine from human 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Duphar Research Laboratories
Curated by ChEMBL
Duphar Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Ability to inhibit [3H]WB-4101 binding to alpha-1 adrenergic receptor was determined in ratMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Duphar Research Laboratories
Curated by ChEMBL
Duphar Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Potency to displace [3H]- WB-4101 from alpha-1 adrenergic receptor in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Ability to inhibit the [3H]spiperone binding to striatum Dopamine receptor D2 was determined in ratMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor determined using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]citalopram form human SRET by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair