Found 574 with Last Name = 'kulkarni' and Initial = 'p' 
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]SR141716A from human CB1R receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]SR141716A from human CB1R receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]SR141716A from human CB1R receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1R receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.6 T: 2°CAssay Description:Supercoiling assay was performed using the commercially available kit (DNA gyrase supercoiling assay kit: SAS4001) from Inspiralis Pvt.limited, Norwi...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bharati Vidyapeeth'S College of Pharmacy
Bharati Vidyapeeth'S College of Pharmacy
Affinity DataIC50: 100nMpH: 7.4Assay Description:The inhibition was carried out in 96-well polystyrene round bottomed
plates. These plates were precoated with 100 ul per well of 50 ug per ml
poly(...More data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMpH: 7.5Assay Description:Initially, equimolar quantities of about 0.5µM each of E. coli gyraseA and S. aureus gyraseB were incubated for a period of 45 min with salmon sperm ...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by subs...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by subs...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bharati Vidyapeeth'S College of Pharmacy
Bharati Vidyapeeth'S College of Pharmacy
Affinity DataIC50: 500nMpH: 7.4Assay Description:The inhibition was carried out in 96-well polystyrene round bottomed
plates. These plates were precoated with 100 ul per well of 50 ug per ml
poly(...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 810nMpH: 7.5Assay Description:Initially, equimolar quantities of about 0.5µM each of E. coli gyraseA and S. aureus gyraseB were incubated for a period of 45 min with salmon sperm ...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of PDE4D2 (unknown origin) using cAMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and incubated for 1...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 940nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 940nMAssay Description:Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by subs...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant His-tagged PDE4B (unknown origin) expressed in Sf9 cells using cAMP as substrate preincubated for 15 mins followed by subst...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B ATPase activityMore data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Hyderabad Campus
Curated by ChEMBL
University Of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by subs...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...More data for this Ligand-Target Pair
