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Found 154 with Last Name = 'kurihara' and Initial = 'm'
TargetMu-type opioid receptor(GUINEA PIG)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  0.0871nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  3nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor delta 1 using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataKi:  7.20nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  12nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  13nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataKi:  60nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor delta 1 using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474149(CHEBI:70073 | Corynanrheidine)
Affinity DataKi:  72nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  79nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  123nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  155nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor delta 1 using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  417nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor delta 1 using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  468nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474149(CHEBI:70073 | Corynanrheidine)
Affinity DataKi:  2.57E+3nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474149(CHEBI:70073 | Corynanrheidine)
Affinity DataKi:  2.88E+3nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor delta 1 using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  2.95E+3nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  3.09E+4nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor delta 1 using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171495(CHEMBL3805318)
Affinity DataIC50:  0.0900nMAssay Description:Antagonist activity at ERalpha (unknown origin) transfected in 17beta-estradiol induced-HEK293 cells assessed as inhibition of estradiol-mediated pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  0.470nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171494(CHEMBL3806167)
Affinity DataIC50:  0.680nMAssay Description:Antagonist activity at ERalpha (unknown origin) transfected in 17beta-estradiol induced-HEK293 cells assessed as inhibition of estradiol-mediated pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171499(CHEMBL3805385)
Affinity DataIC50:  1.80nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme in Hog plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50092526(CHEMBL3586195)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50092484(CHEMBL3586191)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50092523(CHEMBL3586193)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)
Affinity DataIC50:  4.90nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human MCF7 cells assessed as inhibition of E2-induced response by dual luciferase report...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171495(CHEMBL3805318)
Affinity DataIC50:  5.90nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)
Affinity DataIC50:  7.30nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171498(CHEMBL3805025)
Affinity DataIC50:  11nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50092522(CHEMBL3586192)
Affinity DataIC50:  11nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50104834(CHEMBL3597499)
Affinity DataIC50:  13nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50092501(CHEMBL3098274)
Affinity DataIC50:  14nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171497(CHEMBL3804907)
Affinity DataIC50:  28nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Mus musculus)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Affinity DataIC50:  33nMAssay Description:Antagonist activity at estrogen receptor in mouse GT1-7 cells harboring beta-galactosidase reporter gene assessed as reduction in 17beta-estradiol in...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50104835(CHEMBL3597498)
Affinity DataIC50:  35nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171494(CHEMBL3806167)
Affinity DataIC50:  40nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171493(CHEMBL3805170)
Affinity DataIC50:  49nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50092483(CHEMBL3586190)
Affinity DataIC50:  53nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50171492(CHEMBL3805921)
Affinity DataIC50:  61nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240314(CHEMBL4059760)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50104800(CHEMBL3597509)
Affinity DataIC50:  94nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50104804(CHEMBL3597505)
Affinity DataIC50:  110nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250101((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-car...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240313(CHEMBL4103516)
Affinity DataIC50:  134nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50092482(CHEMBL3098273)
Affinity DataIC50:  151nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240312(CHEMBL4075785)
Affinity DataIC50:  154nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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