TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Mixed-type inhibition of electric eel AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 200nMpH: 7.2Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in sodium phosphate buffer (50 mM, pH 7.2) and a 1 cm pathlengt...More data for this Ligand-Target Pair
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 300nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
Affinity DataKi: 800nMpH: 7.2Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in sodium phosphate buffer (50 mM, pH 7.2) and a 1 cm pathlengt...More data for this Ligand-Target Pair
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 1.50E+3nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMpH: 7.2Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in sodium phosphate buffer (50 mM, pH 7.2) and a 1 cm pathlengt...More data for this Ligand-Target Pair
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 6.10E+4nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 6.30E+4nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 1.40E+5nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataKi: 4.20E+5nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Respiratory syncytial virus fusion proteinMore data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Respiratory syncytial virus fusion proteinMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Respiratory syncytial virus fusion proteinMore data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Respiratory syncytial virus fusion proteinMore data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Reviral
Curated by ChEMBL
Reviral
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Respiratory syncytial virus A2 fusion protein expressed in HEK293T cells harboring GAL4-NF-kappaB assessed as reduction in cell-cell fu...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 6 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 6 mins followed by substrate addition measured up to 180 s...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair