Affinity DataIC50: 1nMAssay Description:Inhibition of full length human PARP1 expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidin-...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of His-tagged FGFR3 V555M mutant (unknown origin) expressed in insect cells using poly Glu-Tyr preincubated for 1 hr followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human PARP2 (2 to 583 residues) expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by strep...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human PARP1 expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidin-...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of HIPK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human PARP2 (2 to 583 residues) expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by strep...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Ikkepsilon using 5FAM-AKELDQGSLCTpSFVGTLQ-NH2 as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length N-terminus His-tagged human CK2alpha expressed in insect Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as substrate after 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length N-terminus His-tagged human CK2alpha expressed in insect Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as substrate after 20 ...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at GST-tagged BIR3 domain of cIAP1 using AbuRPFK-5FAM after 20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Aurora B kinaseMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of Ikkepsilon using 5FAM-AKELDQGSLCTpSFVGTLQ-NH2 as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal His6X-tagged recombinant human full length casein kinase-2alpha expressed in SF21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as ...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Aurora B kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of full length N-terminus His-tagged human CK2alpha expressed in insect Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as substrate after 20 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human TNKS1 (1001 to 1327 residues) expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by s...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by ChEMBL
Astrazeneca R&D Boston
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair