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Found 536 with Last Name = 'le grand' and Initial = 'd'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390424(CHEMBL2071340)
Affinity DataKi:  3nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110delta using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390409(CHEMBL1986603)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110delta using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390408(CHEMBL2071338)
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390426(CHEMBL2071329)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076828(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  12nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073296(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076819(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  13nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073308(4-[(R)-2-(4-Methoxy-phenyl)-1-methyl-ethylamino]-p...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076823(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  16nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073302(4-((S)-2-Cyclohexyl-1-hydroxymethyl-ethylamino)-py...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073307(4-((R)-1-Methyl-2-phenyl-ethylamino)-pyridine-3-su...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390419(CHEMBL2071333)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110delta using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073297(4-[(S)-1-(4-Hydroxy-piperidin-1-ylmethyl)-2-phenyl...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073290(4-{(S)-1-Benzyl-2-[bis-(2-methoxy-ethyl)-amino]-et...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073283(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073283(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  19nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073283(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  19nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073297(4-[(S)-1-(4-Hydroxy-piperidin-1-ylmethyl)-2-phenyl...)
Affinity DataKi:  19nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390423(CHEMBL2071337)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390425(CHEMBL2071341)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110gamma using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073298(4-((S)-1-Benzyl-2-morpholin-4-yl-ethylamino)-pyrid...)
Affinity DataKi:  22nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073298(4-((S)-1-Benzyl-2-morpholin-4-yl-ethylamino)-pyrid...)
Affinity DataKi:  22nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073298(4-((S)-1-Benzyl-2-morpholin-4-yl-ethylamino)-pyrid...)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073287(4-[(S)-2-(4-Acetyl-piperazin-1-yl)-1-benzyl-ethyla...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073294(4-((S)-1-Benzyl-2-dimethylamino-ethylamino)-pyridi...)
Affinity DataKi:  24nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073294(4-((S)-1-Benzyl-2-dimethylamino-ethylamino)-pyridi...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073305(4-((S)-1-Benzyl-2-piperidin-1-yl-ethylamino)-pyrid...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076837(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  26nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073306(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  27nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390418(CHEMBL2071332)
Affinity DataKi:  28nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50075870(4-[(S)-1-(2-Hydroxy-ethoxymethyl)-2-phenyl-ethylam...)
Affinity DataKi:  28nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390419(CHEMBL2071333)
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390426(CHEMBL2071329)
Affinity DataKi:  32nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110gamma using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073299(4-((S)-2-Cyclohexyl-1-methylaminomethyl-ethylamino...)
Affinity DataKi:  33nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390415(CHEMBL2071328)
Affinity DataKi:  35nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073288(4-((S)-1-Methylaminomethyl-2-phenyl-ethylamino)-py...)
Affinity DataKi:  35nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390411(CHEMBL2071342)
Affinity DataKi:  36nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110gamma using [32P]ATP after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076830(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  36nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073304(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  36nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073295(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  39nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073295(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  39nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073295(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  39nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50075873(4-[(S)-1-Hydroxymethyl-2-(4-methoxy-phenyl)-ethyla...)
Affinity DataKi:  40nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073293(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  41nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076824(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  41nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50076821(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  43nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073286(4-((S)-1-Butylaminomethyl-2-phenyl-ethylamino)-pyr...)
Affinity DataKi:  43nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50390417(CHEMBL2071331)
Affinity DataKi:  45nMAssay Description:Inhibition of recombinant GST-tagged PI3K p110alpha by KinaseGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073309(4-((S)-1-Benzyl-2-diethylamino-ethylamino)-pyridin...)
Affinity DataKi:  45nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50073303(4-((S)-2-Phenyl-1-propylaminomethyl-ethylamino)-py...)
Affinity DataKi:  47nMAssay Description:In vitro binding affinity for human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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