Affinity DataKi: 0.0100nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0270nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0660nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0710nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0810nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in HEK293 cell membranes incubated for 2 hrs and measured by gamma countin...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat alpha7 nAChR expressed in HEK293 cell membranes incubated for 2 hrs and measured by gamma counting ...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I]Tyr54-alpha-bungarotoxin from rat alpha7 nAChR expressed in HEK293 cell membranes co-expressing human RIC3 measured after 2 hrs...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat alpha7 nAChR expressed in HEK293 cell membranes incubated for 2 hrs and measured by gamma counting ...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in HEK293 cell membranes incubated for 2 hrs and measured by gamma countin...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 25nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Displacement of [125I]Tyr54-alpha-bungarotoxin from rat alpha7 nAChR expressed in HEK293 cell membranes co-expressing human RIC3 measured after 2 hrs...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 43nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 59nMpH: 6.4Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 6.4 after 1.5 hrs by Microbeta liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 78nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 92nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat hippocampal alpha7 nAChR measured after 2 hrs by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 92nMpH: 6.4Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 6.4 after 1.5 hrs by Microbeta liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataKi: 100nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 110nMpH: 6.4Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 6.4 after 1.5 hrs by Microbeta liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataKi: 110nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMpH: 5.0Assay Description:Displacement of [3H]BMS-599240 from BACE1 (unknown origin) expressed in HEK293 cells at pH 5 after 1.5 hrs by Microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair