TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform); Range is 6-10 nMMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I isoform); Range is 33-37 nMMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 470nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 890nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 950nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
Affinity DataKi: 2.23E+3nMAssay Description:Inhibitory constant was determined in an HIV-1 reverse transcriptase assay in which the [3H]dTTP concentration was varied (i.e. 40, 20, 10, 6, and 4 ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in mouse L cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in human Daudi lymphoblastoid cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in rabbit reticulocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Compound concentration that causes 50 % inhibition of HIV-1 peptide-derived reverse transcriptase (RT) obtained from HIV-1-infected H9 cell culturesMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in human Daudi lymphoblastoid cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in mouse L cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Compound concentration that causes 50 % inhibition of HIV-1 peptide-derived reverse transcriptase (RT)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in rabbit reticulocytesMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataIC50: 6.95E+3nMAssay Description:Compound concentration that causes 50 % inhibition of HIV-1 peptide-derived reverse transcriptase (RT)More data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.75E+5nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair