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Found 61 with Last Name = 'lim-wilby' and Initial = 'ms'
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  0.467nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  0.505nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  0.505nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076073(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  6.20nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  6.20nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076070(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  8nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  21nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  26nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076069(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  51nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076068(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  89nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076069(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  103nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076070(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  135nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  141nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076068(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  188nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  194nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076066(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  203nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076069(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  250nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  256nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  257nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  396nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  447nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076072(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  472nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076066(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  479nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076073(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  791nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  791nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  905nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076072(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  1.22E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  1.22E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076068(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  2.36E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076072(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076070(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076072(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076069(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076066(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076068(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: >2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
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