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Found 52 with Last Name = 'lisowski' and Initial = 'v'
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073221(CHEMBL3408420)
Affinity DataKi:  2.70E+4nMAssay Description:Competitive inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073222(CHEMBL3125572)
Affinity DataKi:  5.06E+4nMAssay Description:Competitive inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50428852(CHEMBL483062)
Affinity DataIC50:  9nMAssay Description:Inhibition of chymotrypsin-like activity of Proteasome subunit beta 5 (unknown origin) assessed as inhibition of beta-amyloid production by cell-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM50103203(3-(3-Hydroxy-4-methoxy-phenyl)-thieno[2,3-b]pyrrol...)
Affinity DataIC50:  1.50E+3nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50103203(3-(3-Hydroxy-4-methoxy-phenyl)-thieno[2,3-b]pyrrol...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory concentration against calf tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM50103203(3-(3-Hydroxy-4-methoxy-phenyl)-thieno[2,3-b]pyrrol...)
Affinity DataIC50:  5.50E+3nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50210949(CHEMBL3946523)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of recombinant human HGK using Ulight-FLGFTYVAP as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85763(Thienopyrrolizine derivative, 4j)
Affinity DataIC50:  1.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85767(Thienopyrrolizine derivative, 4n)
Affinity DataIC50:  1.10E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85770(Thienopyrrolizine derivative, 13g)
Affinity DataIC50:  1.20E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85763(Thienopyrrolizine derivative, 4j)
Affinity DataIC50:  1.70E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85770(Thienopyrrolizine derivative, 13g)
Affinity DataIC50:  1.90E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50474787(CHEMBL33138)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory concentration against calf tubulin polymerizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50474786(CHEMBL285735)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory concentration against calf tubulin polymerizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85767(Thienopyrrolizine derivative, 4n)
Affinity DataIC50:  2.30E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073221(CHEMBL3408420)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50210945(CHEMBL3955556)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of recombinant human HGK using Ulight-FLGFTYVAP as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85760(Thienopyrrolizine derivative, 4c)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM50240449(3-(3-(benzyloxy)-4-methoxyphenyl)-8H-thieno[2,3-b]...)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85768(Thienopyrrolizine derivative, 5)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85761(Thienopyrrolizine derivative, 4h)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85762(Thienopyrrolizine derivative, 4i)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85766(Thienopyrrolizine derivative, 4m)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85764(Thienopyrrolizine derivative, 4k)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85766(Thienopyrrolizine derivative, 4m)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85765(Thienopyrrolizine derivative, 4l)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85769(Thienopyrrolizine derivative, 13e)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85764(Thienopyrrolizine derivative, 4k)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85765(Thienopyrrolizine derivative, 4l)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85762(Thienopyrrolizine derivative, 4i)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85761(Thienopyrrolizine derivative, 4h)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85769(Thienopyrrolizine derivative, 13e)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85758(Thienopyrrolizine derivative, 4a)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85759(Thienopyrrolizine derivative, 4b)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85758(Thienopyrrolizine derivative, 4a)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85759(Thienopyrrolizine derivative, 4b)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM85760(Thienopyrrolizine derivative, 4c)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
UniversitÉ

LigandPNGBDBM50240449(3-(3-(benzyloxy)-4-methoxyphenyl)-8H-thieno[2,3-b]...)
Affinity DataIC50: >5.00E+4nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073228(CHEMBL3408421)
Affinity DataIC50:  5.57E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073222(CHEMBL3125572)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073230(CHEMBL3125570)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073231(CHEMBL3125571)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073229(CHEMBL3408419)
Affinity DataIC50:  8.09E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073233(CHEMBL3408416)
Affinity DataIC50:  8.39E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073232(CHEMBL3408410)
Affinity DataIC50:  9.59E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50210946(CHEMBL3893977)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human HGK using Ulight-FLGFTYVAP as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50210947(CHEMBL3125569)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human HGK using Ulight-FLGFTYVAP as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50210950(CHEMBL3973327)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human HGK using Ulight-FLGFTYVAP as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50210948(CHEMBL3919199)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human HGK using Ulight-FLGFTYVAP as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073227(CHEMBL3408430)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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