Affinity DataKi: 78nMAssay Description:Displacement of [3H]-mibolerone from GST-tagged human AR-LBD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 267nMAssay Description:Displacement of [3H]-mibolerone from GST-tagged human AR-LBD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nM ΔG°: -31.2kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Affinity DataKi: 3.64E+3nMAssay Description:Displacement of [3H]-mibolerone from GST-tagged human AR-LBD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nM ΔG°: -30.6kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 1.30E+4nM ΔG°: -27.7kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 1.40E+4nM ΔG°: -27.5kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 1.60E+4nM ΔG°: -27.2kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 2.30E+4nM ΔG°: -26.3kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 3.50E+4nM ΔG°: -25.3kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 4.40E+4nM ΔG°: -24.7kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Affinity DataKi: 5.10E+4nM ΔG°: -24.3kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Affinity DataKi: 8.70E+4nM ΔG°: -23.0kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Affinity DataKi: 1.55E+5nM ΔG°: -21.6kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 3.37E+5nM ΔG°: -19.7kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 4.23E+5nM ΔG°: -19.1kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 1.09E+6nM ΔG°: -16.8kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Affinity DataKi: 1.35E+6nM ΔG°: -16.3kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University of Alabama At Birmingham
University of Alabama At Birmingham
Affinity DataKi: 1.78E+6nM ΔG°: -15.6kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human NNMT in human K562 cells measured after 24 hrs by quantitative mass spectrometryMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair