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Found 12 with Last Name = 'lucantoni' and Initial = 'l'
TargetAminopeptidase N(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50518449(CHEMBL4435950)
Affinity DataKi:  300nMAssay Description:Inhibition of human APN expressed in HEK293 cells preincubated for 20 mins followed by L-leucine-7-amido-4-methylcoumarin addition by fluorescence as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of MMP2 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of MMP9 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50399931(CHEMBL2181207)
Affinity DataIC50:  22nMAssay Description:Inhibition of human ERG expressed in rat after 2 to 3 days by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50518450(CHEMBL4591371)
Affinity DataIC50:  190nMAssay Description:Inhibition of MMP2 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50518450(CHEMBL4591371)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of MMP9 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChloroquine resistance transporter(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM519((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes assessed as reduction in [3H]-chloroquine uptak...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50518449(CHEMBL4435950)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of MMP2 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50573976(CHEMBL4874145)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG by QPatch automated patch clamp systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChloroquine resistance transporter(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50338982((R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes assessed as reduction in [3H]-chloroquine uptak...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChloroquine resistance transporter(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50399930(CHEMBL2181208)
Affinity DataIC50:  2.28E+5nMAssay Description:Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes assessed as reduction in [3H]-chloroquine uptak...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50518449(CHEMBL4435950)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of MMP9 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed