Compile Data Set for Download or QSAR
maximum 50k data
Found 9805 with Last Name = 'mak' and Initial = 'cc'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataKi:  0.0620nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221559(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221565(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221557((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221562(4-(7-(2-bromo-5-hydroxyphenyl)-5-methylbenzo[e][1,...)
Affinity DataKi:  1nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221549(4-(7-(6-chloro-2-fluoro-3-hydroxyphenyl)-5-methylb...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221563((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221555(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221558(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221560(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataKi:  3nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221550(4-(7-(2,6-difluoro-3-hydroxyphenyl)-5-methylbenzo[...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221561(4-chloro-3-(3-(4-(1-(2-(diethylamino)ethyl)piperid...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221552(CHEMBL249819 | US8481536, 545 | {4-[7-(2-chloro-5-...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221551(4-chloro-3-(5-methyl-3-(4-(piperazin-1-ylsulfonyl)...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198826(4-(7-(2-chloro-6-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataKi:  5nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221564(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)
Affinity DataKi:  7nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221554(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataKi:  7.70nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)
Affinity DataKi:  11nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  11nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  12.9nMAssay Description:Inhibition of Yes kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198786(4-(7-(5-amino-2-chlorophenyl)-5-methylbenzo[e][1,2...)
Affinity DataKi:  16nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  19.4nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  20nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221548(4-(7-(1H-indol-4-yl)-5-methylbenzo[e][1,2,4]triazi...)
Affinity DataKi:  24nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  25.9nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221546(4-(7-(2,6-dichloro-3-hydroxyphenyl)-5-methylbenzo[...)
Affinity DataKi:  27nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  28.1nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  29.4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198813(7-(2-chlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-...)
Affinity DataKi:  35nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198813(7-(2-chlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-...)
Affinity DataKi:  42nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  63.8nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  407nMAssay Description:Inhibition of RetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  493nMAssay Description:Inhibition of FGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  784nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  2.09E+3nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183286(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-N,...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183304(CHEMBL380487 | N-(2-cyanoethyl)-N-ethyl-4-(1,1,1,3...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  0.5nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97975(US8481536, 565)
Affinity DataIC50:  0.542nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97937(US8481536, 507 | US8481536, 612)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221549(4-(7-(6-chloro-2-fluoro-3-hydroxyphenyl)-5-methylb...)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183290(CHEMBL205506 | pyrrolidin-1-yl-[4-(2,2,2-trifluoro...)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97969(US8481536, 559)
Affinity DataIC50:  0.955nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM50183294(CHEMBL204287 | piperidin-1-yl-[4-(2,2,2-trifluoro-...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 9805 total ) | Next | Last >>
Jump to: