Found 313 with Last Name = 'manglik' and Initial = 'a' TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 0.930nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 3.70nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 3.70nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 4.10nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 4.10nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 4.5nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 4.70nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 5.60nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 5.90nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 5.90nMAssay Description:This study supports a structure-based approach for GPCR ligand discovery. These new chemotypes may stabilize receptor conformations not explored prev...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 6.20nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 6.5nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:This study supports a structure-based approach for GPCR ligand discovery. These new chemotypes may stabilize receptor conformations not explored prev...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 7.70nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 8.30nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 12nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 12nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 14nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 17nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 18nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 18nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 19nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 22nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 22nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 23nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 25nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 25nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 27nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 27nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 27nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
3D Structure (crystal)TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 29nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 32nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 32nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 34nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 34nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 35nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:This study supports a structure-based approach for GPCR ligand discovery. These new chemotypes may stabilize receptor conformations not explored prev...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 36nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 37nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 37nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 38nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 38nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 41nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 42nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 42nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 42nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 42nMAssay Description:For a primary screen of selected molecules, binding to μOR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). ...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 43nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 43nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
TargetMu-type opioid receptor [N127C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataKi: 43nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
