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Found 14 with Last Name = 'martinez' and Initial = 'ej'
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)
Affinity DataIC50:  9.93E+3nMAssay Description:Inhibition of methyl-transferase activity in GST-tagged recombinant SET7/9 (unknown origin) expressed in Escherichia coli BL21 using H3(1-20)-cys-bio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of 10 nM SET7 (unknown origin)-mediated methylation of histone H3(1-20)cys-biotin at 15 to 50 uM after 5 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of 100 nM SET7 (unknown origin)-mediated methylation of histone H3(1-20)cys-biotin at 15 to 50 uM after 5 mins by scintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of 50 nM SET7 (unknown origin)-mediated methylation of histone H3(1-20)cys-biotin at 15 to 50 uM after 5 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of SET7 (unknown origin)-mediated methylation of histone H3(1-20)cys-biotin after 5 mins by scintillation proximity assay in presence of [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)
Affinity DataIC50:  2.64E+4nMAssay Description:Inhibition of C-terminal GST-tagged human G9a-mediated-methylation of histone3 expressed in Escherichia coli BL21(DE3) by MALDI-TOF mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Rgenix

US Patent
LigandPNGBDBM26066(2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophe...)
Affinity DataEC50:  179nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Rgenix

US Patent
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  50nMAssay Description:TBDMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Rgenix

US Patent
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Rgenix

US Patent
LigandPNGBDBM426493(US10543183, Compound SB742881 | US10669296, Compou...)
Affinity DataEC50:  25nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Rgenix

US Patent
LigandPNGBDBM426493(US10543183, Compound SB742881 | US10669296, Compou...)
Affinity DataEC50:  74nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Rgenix

US Patent
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  40nMAssay Description:TBDMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Rgenix

US Patent
LigandPNGBDBM26066(2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophe...)
Affinity DataEC50:  24nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Rgenix

US Patent
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  200nMAssay Description:TBDMore data for this Ligand-Target Pair