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Found 50 with Last Name = 'mascaretti' and Initial = 'oa'
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281044((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  50nMAssay Description:Compound was tested in vitro for its ability to inhibit human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285111((2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  130nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281044((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285107((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  490nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285106((2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  540nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285112((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-trifluorome...)
Affinity DataIC50:  680nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285109((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-trifluorome...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285107((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285111((2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285106((2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.40E+4nMAssay Description:Compound was tested in vitro for its ability to inhibit human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285102(2,2-Dimethyl-propionic acid (2S,5R,6S)-6-chloro-3,...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285108((2S,5R,6S)-6-Fluorosulfonyloxy-3,3-dimethyl-4,4,7-...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285102(2,2-Dimethyl-propionic acid (2S,5R,6S)-6-chloro-3,...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281044((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021954((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021954((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285103(Acetic acid (2S,5R,6S)-6-chloro-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285103(Acetic acid (2S,5R,6S)-6-chloro-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285117((2S,3R,5R,6S)-6-Chloro-3-chloromethyl-3-methyl-4,4...)
Affinity DataIC50:  7.00E+4nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285121((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  2.00E+5nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  2.05E+5nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285101((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285115((2S,3R,5R)-3-Chloromethyl-3-methyl-4,4,7-trioxo-4l...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285101((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285115((2S,3R,5R)-3-Chloromethyl-3-methyl-4,4,7-trioxo-4l...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285117((2S,3R,5R,6S)-6-Chloro-3-chloromethyl-3-methyl-4,4...)
Affinity DataIC50:  4.50E+5nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285105((2S,5R,6R)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  9.50E+5nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285105((2S,5R,6R)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  9.50E+5nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285119((2S,3R,5R,6S)-6-Bromo-3-chloromethyl-3-methyl-7-ox...)
Affinity DataIC50:  1.00E+6nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285113((2S,3R,5R,6S)-6-Bromo-3-chloromethyl-3-methyl-4,4,...)
Affinity DataIC50:  1.00E+6nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285104((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.16E+6nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285110((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.20E+6nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285104((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.21E+6nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285110((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285121((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.50E+6nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285120((2S,3R,5R,6S)-3-Chloromethyl-6-fluoro-3-methyl-4,4...)
Affinity DataIC50: >3.00E+6nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285120((2S,3R,5R,6S)-3-Chloromethyl-6-fluoro-3-methyl-4,4...)
Affinity DataIC50: >3.00E+6nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285113((2S,3R,5R,6S)-6-Bromo-3-chloromethyl-3-methyl-4,4,...)
Affinity DataIC50:  3.00E+6nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285122((2S,3R,5R,6S)-3-(Benzothiazol-2-ylsulfanylmethyl)-...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285123((2S,3R,5R,6S)-3-(Benzothiazol-2-ylsulfanylmethyl)-...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285116((2S,3R,5R,6S)-3-Chloromethyl-6-fluoro-3-methyl-7-o...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285118((2S,3R,5R,6S)-3-(Benzothiazol-2-ylsulfanylmethyl)-...)
Affinity DataIC50: >5.00E+6nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285119((2S,3R,5R,6S)-6-Bromo-3-chloromethyl-3-methyl-7-ox...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285114((2S,3R,5R,6S)-6-Chloro-3-chloromethyl-3-methyl-7-o...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285122((2S,3R,5R,6S)-3-(Benzothiazol-2-ylsulfanylmethyl)-...)
Affinity DataIC50: >5.00E+6nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285118((2S,3R,5R,6S)-3-(Benzothiazol-2-ylsulfanylmethyl)-...)
Affinity DataIC50: >5.00E+6nMAssay Description:Tested for the ability to inhibit Beta-lactamase of Bacillus cereus (class A enzyme) with 10 minutes preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285123((2S,3R,5R,6S)-3-(Benzothiazol-2-ylsulfanylmethyl)-...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase 1(Bacillus cereus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285114((2S,3R,5R,6S)-6-Chloro-3-chloromethyl-3-methyl-7-o...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Beta-lactamase of Bacillus cereus (class A enzyme) without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article