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Found 179 with Last Name = 'mccague' and Initial = 'r'
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50228778(4,4''-Dihydroxyoctafluoroazobenzene | CHEMBL79036)
Affinity DataKi:  4.00E+3nMpH: 7.4Assay Description:Binding constant of Testosterone-5 alpha-reductase activity at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(2,3,5,6-Tetrafluoro-4-pentafluorophenylazo-phenol ...)
Affinity DataKi:  1.00E+4nMpH: 7.4Assay Description:Inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029237(2-Pyridin-4-yl-propionic acid (S)-2,6,6-trimethyl-...)
Affinity DataIC50:  6nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029237(2-Pyridin-4-yl-propionic acid (S)-2,6,6-trimethyl-...)
Affinity DataIC50:  6nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029228(2-Pyridin-4-yl-butyric acid (S)-2,6,6-trimethyl-bi...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029228(2-Pyridin-4-yl-butyric acid (S)-2,6,6-trimethyl-bi...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029240(2-Methyl-2-pyridin-4-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029229(2-Methyl-2-pyridin-3-yl-propionic acid adamantan-1...)
Affinity DataIC50:  13nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029229(2-Methyl-2-pyridin-3-yl-propionic acid adamantan-1...)
Affinity DataIC50:  13nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029230(2-Methyl-2-pyridin-3-yl-propionic acid 2-methyl-ad...)
Affinity DataIC50:  13nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  14nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029241(2-Pyridin-3-yl-propionic acid (S)-2,6,6-trimethyl-...)
Affinity DataIC50:  14nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029242(2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  15nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029242(2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  15nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029240(2-Methyl-2-pyridin-4-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  26nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029226(2-Pyridin-3-yl-propionic acid adamantan-1-yl ester...)
Affinity DataIC50:  35nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029226(2-Pyridin-3-yl-propionic acid adamantan-1-yl ester...)
Affinity DataIC50:  35nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029236(2-Ethyl-2-pyridin-4-yl-butyric acid (S)-2,6,6-trim...)
Affinity DataIC50:  35nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029227(CHEMBL135095 | Pyridin-3-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  38nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029227(CHEMBL135095 | Pyridin-3-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  38nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029242(2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  47nMAssay Description:Inhibition of rat testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029242(2-Methyl-2-pyridin-3-yl-propionic acid (S)-2,6,6-t...)
Affinity DataIC50:  52nMAssay Description:Inhibition of rat testicular C17,20-LyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029232(CHEMBL134442 | Pyridin-4-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  52nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  65nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  65nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029230(2-Methyl-2-pyridin-3-yl-propionic acid 2-methyl-ad...)
Affinity DataIC50:  75nMAssay Description:Tested for inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029230(2-Methyl-2-pyridin-3-yl-propionic acid 2-methyl-ad...)
Affinity DataIC50:  75nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029241(2-Pyridin-3-yl-propionic acid (S)-2,6,6-trimethyl-...)
Affinity DataIC50:  82nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029239(CHEMBL131984 | Pyridin-3-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  88nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014462(CHEMBL104047 | Pyridin-4-yl-acetic acid adamantan-...)
Affinity DataIC50:  89nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014449((1R,2R,3R,5S)-(-)-Pyridin-4-yl-acetic acid 2,6,6-t...)
Affinity DataIC50:  96nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014449((1R,2R,3R,5S)-(-)-Pyridin-4-yl-acetic acid 2,6,6-t...)
Affinity DataIC50:  96nMAssay Description:Concentration required to inhibit 50% activity of rat testicular Cytochrome P450 steroid 17alpha-hydroxylase/17,20 lyase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014456((+)-Pyridin-4-yl-acetic acid 1,7,7-trimethyl-bicyc...)
Affinity DataIC50:  97nMAssay Description:Concentration required to inhibit 50% activity of rat testicular Cytochrome P450 steroid 17alpha-hydroxylase/17,20 lyase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014456((+)-Pyridin-4-yl-acetic acid 1,7,7-trimethyl-bicyc...)
Affinity DataIC50:  97nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014457(CHEMBL101743 | Pyridin-4-yl-acetic acid 4-ethyl-cy...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  120nMAssay Description:Tested for inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029233(CHEMBL135037 | Pyridin-3-yl-acetic acid adamantan-...)
Affinity DataIC50:  130nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029236(2-Ethyl-2-pyridin-4-yl-butyric acid (S)-2,6,6-trim...)
Affinity DataIC50:  140nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014451((+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014451((+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029239(CHEMBL131984 | Pyridin-3-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  260nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  260nMAssay Description:Inhibition of rat testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029232(CHEMBL134442 | Pyridin-4-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  270nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of rat testicular C17,20-LyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014448(CHEMBL102409 | Pyridin-4-yl-acetic acid cyclohexyl...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50014458(CHEMBL102884 | Pyridin-4-yl-acetic acid 4-tert-but...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029235(CHEMBL3084924 | Pyridin-3-yl-acetic acid 2-methyl-...)
Affinity DataIC50:  320nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50003134(3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...)
Affinity DataIC50:  330nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029232(CHEMBL134442 | Pyridin-4-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  440nMAssay Description:Tested for inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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