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Found 670 with Last Name = 'mcmahon' and Initial = 'g'
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50016816(CHEMBL412913 | S-S-C-F-G-G-R-I-D-R-I-G-A-Q-S-G-L-G...)
Affinity DataKi:  0.25nMAssay Description:Apparent binding affinity for non-vasorelaxant receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50452851(CHEMBL2373017)
Affinity DataIC50:  0.900nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50228335(CHEMBL263034)
Affinity DataIC50:  1.30nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50030815(CHEMBL404594)
Affinity DataIC50:  1.90nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor from rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50228272(CHEMBL411997)
Affinity DataIC50:  2.10nMAssay Description:pA2 value for Angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50228195(Angiotensin Ii | CHEBI:2719)
Affinity DataIC50:  2.20nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50228308(CHEMBL413740)
Affinity DataIC50:  2.60nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044356(5-Butyl-2-phenethyl-4-[2'-(1H-tetrazol-5-yl)-biphe...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044345(5-Butyl-2-(2-hydroxy-2-phenyl-ethyl)-4-[2'-(1H-tet...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4917((3Z)-3-{[3-(2-carboxyethyl)-4,5,6,7-tetrahydro-1H-...)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4915(3-(2-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-y...)
Affinity DataIC50:  4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044334(5-{3-Butyl-5-oxo-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044355(2,5-Dibutyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl...)
Affinity DataIC50:  5nMAssay Description:Displacement of [125-I]-labeled angiotensin II from Angiotensin II receptor, type 1 of rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044355(2,5-Dibutyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044357(5-Butyl-2-pentyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50046078(5-[4'-(3,5-Dibutyl-[1,2,4]triazol-1-ylmethyl)-biph...)
Affinity DataIC50:  6.5nMAssay Description:Activity against high affinity Angiotensin II receptor, type 1 was measured from the ability to inhibit [125I]-angiotensin II binding to rat uterine ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044348(5-Butyl-2-(2-oxo-2-phenyl-ethyl)-4-[2'-(1H-tetrazo...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044367(5-Butyl-2-hexyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044361(CHEMBL67764 | {3-Butyl-5-oxo-4-[2'-(1H-tetrazol-5-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044338(6-{3-Butyl-5-oxo-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50228309(CHEMBL408560)
Affinity DataIC50:  10nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044366(5-Butyl-2-sec-butyl-4-[2'-(1H-tetrazol-5-yl)-biphe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4900(3-(2,4-dimethyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydr...)
Affinity DataIC50:  10nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50283548(1-{(5S,8S)-3-Butyl-1-chloro-5-[2'-(2H-tetrazol-5-y...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [125-I]-labeled angiotensin II binding to AT1 receptor in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044365(5-Butyl-2-(2-methoxy-2-phenyl-ethyl)-4-[2'-(2H-tet...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044369(5-{3-Butyl-5-oxo-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50228312(CHEMBL405557)
Affinity DataIC50:  13nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50283551(1-{(5S,8S)-3-Butyl-5-[2'-(2H-tetrazol-5-yl)-biphen...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [125-I]-labeled angiotensin II binding to AT1 receptor in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50228271(CHEMBL268506)
Affinity DataIC50:  15nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044346(5-Butyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044341(5-Butyl-2-(2-ethoxy-2-phenyl-ethyl)-4-[2'-(2-methy...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044335(5-Butyl-2-cyclopropylmethyl-4-[2'-(1H-tetrazol-5-y...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  16nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044344(2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044332(CHEMBL307310 | {3-Butyl-5-oxo-4-[2'-(1H-tetrazol-5...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044340(6-{3-Butyl-5-oxo-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044333(5-Butyl-2-(2-cyclohexyl-ethyl)-4-[2'-(1H-tetrazol-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044364(5-Butyl-2-(3-phenyl-propyl)-4-[2'-(1H-tetrazol-5-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4907((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4882((Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)met...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4882((Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)met...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50228310(CHEMBL403983)
Affinity DataIC50:  20nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4917((3Z)-3-{[3-(2-carboxyethyl)-4,5,6,7-tetrahydro-1H-...)
Affinity DataIC50:  20nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044351(5-Butyl-2-isopropyl-4-[2'-(1H-tetrazol-5-yl)-biphe...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044347(5-Butyl-2-[2-(2,5-dimethoxy-phenyl)-2-oxo-ethyl]-4...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044343(5-Butyl-2-ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044370(5-Butyl-2-[2-(2,5-dimethoxy-phenyl)-2-hydroxy-ethy...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044342(2-(2-Adamantan-1-yl-2-oxo-ethyl)-5-butyl-4-[2'-(1H...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4906((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044359((2-{3-Butyl-4-[2'-(2,3-dihydro-1H-tetrazol-5-yl)-b...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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