Compile Data Set for Download or QSAR
maximum 50k data
Found 186 with Last Name = 'menard' and Initial = 'k'
TargetInsulin-like growth factor 1 receptor(Rattus norvegicus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50318112((S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(...)
Affinity DataKi:  28nMAssay Description:Inhibition of rat IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297163(2-{8-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of BRD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566615(CHEMBL4846895)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297236(2-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-methoxy-5-...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297163(2-{8-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297163(2-{8-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566615(CHEMBL4846895)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566614(CHEMBL4848871)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297070(5-{7-Methanesulfonyl-5-[(S)-oxan-4-yl(phenyl)methy...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566614(CHEMBL4848871)
Affinity DataIC50:  1nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50586606(CHEMBL5080354)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297144(2-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-9-methoxy-5-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297162(2-{6-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50:  1nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074693(CHEMBL3410162)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074771(CHEMBL3410153)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074796(CHEMBL3410169)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074818(CHEMBL3410163)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074771(CHEMBL3410153)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074799(CHEMBL3410167)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074796(CHEMBL3410169)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074694(CHEMBL3410161)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch2 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566613(CHEMBL4864173)
Affinity DataIC50:  1nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297146(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297268(2-{6-Chloro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297146(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297146(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human BRD3 measured by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566613(CHEMBL4864173)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566610(CHEMBL4857742)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297146(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297146(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human BRD2 measured by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566612(CHEMBL4869203)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50594425(CHEMBL5189057)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50586604(CHEMBL5093440)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297163(2-{8-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of BRD3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566610(CHEMBL4857742)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM296886(2-[3-(Dimethyl-1,2-oxazol-4-yl)-5-[oxan-4-yl(pheny...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human BRD2 measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297070(5-{7-Methanesulfonyl-5-[(S)-oxan-4-yl(phenyl)methy...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50586607(CHEMBL5082474)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM296886(2-[3-(Dimethyl-1,2-oxazol-4-yl)-5-[oxan-4-yl(pheny...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM296886(2-[3-(Dimethyl-1,2-oxazol-4-yl)-5-[oxan-4-yl(pheny...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human BRD3 measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297163(2-{8-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50:  2nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074795(CHEMBL3410170)
Affinity DataIC50:  2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074798(CHEMBL3410168)
Affinity DataIC50:  2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074799(CHEMBL3410167)
Affinity DataIC50:  2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074784(CHEMBL3410151)
Affinity DataIC50:  2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074818(CHEMBL3410163)
Affinity DataIC50:  2nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074798(CHEMBL3410168)
Affinity DataIC50:  2nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074795(CHEMBL3410170)
Affinity DataIC50:  2nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299143((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 186 total ) | Next | Last >>
Jump to: