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Found 174 with Last Name = 'mizuno' and Initial = 'm'
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392953(CHEMBL2152353)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant renin compound treated for 10 mins before substrate addition measured after 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant renin compound treated for 10 mins before substrate addition measured after 90 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392953(CHEMBL2152353)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human plasma renin activity after 60 mins by competitive RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human plasma renin activity after 60 mins by competitive RIAMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049128(5-(1-Hydroxy-ethyl)-2-propyl-3-[2'-(2H-tetrazol-5-...)
Affinity DataIC50:  4.90nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50184499(CHEMBL208638 | N-(2-(3-(4-(aminomethyl)phenyl)prop...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049118(2-Ethyl-5-(1-hydroxy-1-methyl-ethyl)-3-[2'-(2H-tet...)
Affinity DataIC50:  5.30nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Macaca fascicularis)
TBA

Curated by ChEMBL
LigandPNGBDBM50392953(CHEMBL2152353)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of cynomolgus monkey plasma renin activity after 60 mins by competitive RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049123(5-Hydroxymethyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-...)
Affinity DataIC50:  6.90nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Macaca fascicularis)
TBA

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  8nMAssay Description:Inhibition of cynomolgus monkey plasma renin activity after 60 mins by competitive RIAMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50241364(4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-te...)
Affinity DataIC50:  8.10nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049107(2-Propyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataIC50:  9.10nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049109(2-Butyl-5-(1-hydroxy-1-methyl-ethyl)-3-[2'-(2H-tet...)
Affinity DataIC50:  9.5nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049124(5-Methyl-2-propyl-3-[2'-(1H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  11nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049116(5-Ethyl-2-propyl-3-(2'-tetrazol-1-yl-biphenyl-4-yl...)
Affinity DataIC50:  12nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50006909(2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50006909(2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  22nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049112(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-(1-hydroxy-et...)
Affinity DataIC50:  28nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049132(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-(1-hydroxy-1-...)
Affinity DataIC50:  28nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049122(2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-(1-hy...)
Affinity DataIC50:  30nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049117(3-(2'-Carboxy-biphenyl-4-ylmethyl)-2-ethyl-5-(1-hy...)
Affinity DataIC50:  37nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049130(5-Isopropyl-2-propyl-3-[2'-(1H-tetrazol-5-yl)-biph...)
Affinity DataIC50:  46nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049113(5-Isopropenyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-bi...)
Affinity DataIC50:  50nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049106(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-(1-hydroxy-1-...)
Affinity DataIC50:  51nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049108(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-hydroxymethyl...)
Affinity DataIC50:  58nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049108(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-hydroxymethyl...)
Affinity DataIC50:  58nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049126(3-(2'-Carboxy-biphenyl-4-ylmethyl)-2-propyl-3H-imi...)
Affinity DataIC50:  60nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50282291(2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-hydro...)
Affinity DataIC50:  65nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50184504(CHEMBL380668 | N-(2-(3-(4-(aminomethyl)phenyl)prop...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049103(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-ethyl-2-propy...)
Affinity DataIC50:  100nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049110(2-Propyl-1-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataIC50:  100nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049129(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-(1-ethyl-1-hy...)
Affinity DataIC50:  110nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049104(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-methyl-2-prop...)
Affinity DataIC50:  110nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  120nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50184505(CHEMBL415045 | N-(2-((3-(4-(aminomethyl)phenyl)pro...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  120nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50009505(2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-chlor...)
Affinity DataIC50:  130nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50009505(2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-chlor...)
Affinity DataIC50:  130nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50184508(CHEMBL207193 | N-(2-(3-(4-(aminomethyl)phenyl)prop...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50282290(3-(2'-Carboxy-biphenyl-4-ylmethyl)-2-ethyl-5-hydro...)
Affinity DataIC50:  150nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50184512(CHEMBL438621 | N-(2-(3-(4-(aminomethyl)phenyl)prop...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50184513(CHEMBL208526 | N-(2-(3-(4-(aminomethyl)phenyl)prop...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049115(5-(1-Hydroxy-1-methyl-ethyl)-2-propyl-3-[2'-(2H-te...)
Affinity DataIC50:  200nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50184514(CHEMBL379328 | N-(2-(3-(4-(aminomethyl)phenyl)prop...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049125(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-isopropenyl-2...)
Affinity DataIC50:  270nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50184500(CHEMBL377266 | N-(2-(3-(4-(aminomethyl)phenyl)prop...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049119(1-(2'-Carboxy-biphenyl-4-ylmethyl)-2-propyl-1H-imi...)
Affinity DataIC50:  320nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049119(1-(2'-Carboxy-biphenyl-4-ylmethyl)-2-propyl-1H-imi...)
Affinity DataIC50:  320nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50049111(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-isopropyl-2-p...)
Affinity DataIC50:  360nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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