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Found 281 with Last Name = 'mohell' and Initial = 'n'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  0.240nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM85827((R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-be...)
Affinity DataKi:  0.260nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50090771((R)-1-[3-(Isopropyl-propyl-amino)-chroman-5-yl]-et...)
Affinity DataKi:  0.300nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50090762((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi:  0.320nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50090763((R)-3-{[4-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-yl)-but...)
Affinity DataKi:  0.340nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50090756((R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxy...)
Affinity DataKi:  0.410nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi:  0.480nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50030418(1-((7R,8S)-7-Dipropylamino-8-methyl-5,6,7,8-tetrah...)
Affinity DataKi:  0.560nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM85190(CAS_3055171 | NAD-299 | NSC_3055171)
Affinity DataKi:  0.590nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50030004(1-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50150685(((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  0.870nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50053667(CHEMBL552643 | Trifluoro-methanesulfonic acid (S)-...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50078242(CHEMBL41491 | [8-(2-Methoxy-phenyl)-chroman-3-yl]-...)
Affinity DataKi:  1.10nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50053661(8-{4-[((R)-5-Fluoro-8-furan-2-yl-1,2,3,4-tetrahydr...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50078243((8-Phenyl-chroman-3-yl)-dipropyl-amine | CHEMBL411...)
Affinity DataKi:  1.10nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50078250(CHEMBL39847 | Dipropyl-(8-thiophen-3-yl-chroman-3-...)
Affinity DataKi:  1.10nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50150676(((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...)
Affinity DataKi:  1.23nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50078240(CHEMBL41200 | [8-(4-Methoxy-phenyl)-chroman-3-yl]-...)
Affinity DataKi:  1.30nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50150678(CHEMBL186758 | [(R)-8-(4-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  1.31nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50150677(CHEMBL188176 | [(S)-5-(4-Methoxy-phenyl)-1,2,3,4-t...)
Affinity DataKi:  1.49nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150680(CHEMBL184535 | [(S)-5-(2-Methoxy-phenyl)-1,2,3,4-t...)
Affinity DataKi:  1.73nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50030025(1-((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50052869((R)-6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibe...)
Affinity DataKi:  1.80nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50053678(((S)-8-Furan-2-yl-1,2,3,4-tetrahydro-naphthalen-2-...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150681(4-(4-Chloro-phenoxy)-1-{2-[(R)-1-(3H-indene-5-sulf...)
Affinity DataKi:  1.99nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50125260(2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...)
Affinity DataKi:  2.24nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50090772((R)-3-(Isobutyl-propyl-amino)-chroman-5-carboxylic...)
Affinity DataKi:  2.37nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50030415(((7R,8S)-7-Dipropylamino-8-methyl-5,6,7,8-tetrahyd...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50051944(3-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150679(CHEMBL186316 | [(R)-8-(2-Methoxy-phenyl)-chroman-3...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50011261((+)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-nap...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150676(((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...)
Affinity DataKi:  2.92nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50090770((R)-Isopropyl-(5-methoxy-chroman-3-yl)-propyl-amin...)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity at 5-HT1A receptor by measuring its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150685(((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  3.38nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Affinity DataKi:  3.79nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50053668(CHEMBL131547 | Dipropyl-((R)-8-trifluoromethanesul...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50078244((3-Dipropylamino-chroman-8-yl)-phenyl-methanone | ...)
Affinity DataKi:  4nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM85826((R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dih...)
Affinity DataKi:  4.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 5A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50051956(2-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...)
Affinity DataKi:  4.90nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50053660(8-{4-[((S)-5-Fluoro-8-methoxy-1,2,3,4-tetrahydro-n...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150684((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...)
Affinity DataKi:  5.29nMAssay Description:Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50053659(CHEMBL441088 | Dipropyl-((S)-8-thiophen-2-yl-1,2,3...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Preclinical R & D, Astra Arcus

Curated by PDSP Ki Database
LigandPNGBDBM50078241((8-Furan-3-yl-chroman-3-yl)-dipropyl-amine | CHEMB...)
Affinity DataKi:  5.70nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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