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Found 133 with Last Name = 'mura' and Initial = 'u'
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataIC50:  9nMpH: 6.9Assay Description:Antagonist activity at NR1/2B receptor (unknown origin) expressed in xenopus laevis at pH 6.9 by two electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334175(2-(2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50:  70nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  96nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50016230(CHEMBL3262478)
Affinity DataIC50:  110nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334181(2-(4-oxo-5-(4-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  110nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50016233(CHEMBL3262475)
Affinity DataIC50:  130nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50016231(CHEMBL3262477)
Affinity DataIC50:  130nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334174(2-(2,4-dioxo-5-(3-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50:  130nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50016232(CHEMBL3262476)
Affinity DataIC50:  130nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  130nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334182(2-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazoli...)
Affinity DataIC50:  150nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50289741(CHEMBL418106 | [3-Oxo-4-(5-trifluoromethyl-benzoth...)
Affinity DataIC50:  150nMAssay Description:Functional antagonism against ETA receptor in rat aortic rings expressed as pA2 valueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  170nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  170nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  170nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50149769((Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  190nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50062613(17-methyl-(1S,9S,10S)-17-azatetracyclo[7.5.3.01,10...)
Affinity DataIC50:  246nMpH: 6.9Assay Description:Antagonist activity at NR1/2B receptor (unknown origin) expressed in xenopus laevis at pH 6.9 by two electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346849(CHEMBL1796882)
Affinity DataIC50:  250nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346847(CHEMBL1796755)
Affinity DataIC50:  270nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334176(2-(5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazolid...)
Affinity DataIC50:  280nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346854(CHEMBL1796887)
Affinity DataIC50:  300nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346848(CHEMBL1796881)
Affinity DataIC50:  350nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  410nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334177(2-(5-(3-methoxybenzylidene)-2,4-dioxothiazolidin-3...)
Affinity DataIC50:  480nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50016234(CHEMBL3262474)
Affinity DataIC50:  500nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50016235(CHEMBL3262473)
Affinity DataIC50:  520nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50016236(CHEMBL3262472)
Affinity DataIC50:  560nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334175(2-(2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50:  820nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346853(CHEMBL1796886)
Affinity DataIC50:  850nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50016237(CHEMBL3262471)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346852(CHEMBL1796885)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334185(5-(3-(benzyloxy)benzylidene)-2-thioxothiazolidin-4...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334184(5-(4-phenoxybenzylidene)-2-thioxothiazolidin-4-one...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  1.21E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346850(CHEMBL1796883)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50077326(CHEMBL55983 | [2-(4-Hydroxy-benzyl)-4-oxo-4H-chrom...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Aldose reductase 2 of bovine lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50077326(CHEMBL55983 | [2-(4-Hydroxy-benzyl)-4-oxo-4H-chrom...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Aldose reductase 2 of bovine lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346851(CHEMBL1796884)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  1.56E+3nMAssay Description:The compound was tested for Inhibitory effect against Aldose reductase 1 in bovine kidneysMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  1.74E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of Aldose reductase 2 of bovine lensMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50274894((Z)-5-(Naphthalen-1'-ylmethylene)-2-thioxothiazoli...)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50077320(7-Hydroxy-2-(4-hydroxy-benzyl)-chromen-4-one | 7-h...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Aldose reductase 2 of bovine lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50346856(CHEMBL1796890)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50202147(5-(3-phenoxybenzylidene)-2-thioxothiazolidin-4-one...)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320782((Z)-5-[(4-Hydroxyphenyl)methylidene]-3-(3,3,3-trif...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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