TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataIC50: 9nMpH: 6.9Assay Description:Antagonist activity at NR1/2B receptor (unknown origin) expressed in xenopus laevis at pH 6.9 by two electrode voltage clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Evaluated for inhibition of Aldose reductase 2More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Functional antagonism against ETA receptor in rat aortic rings expressed as pA2 valueMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataIC50: 246nMpH: 6.9Assay Description:Antagonist activity at NR1/2B receptor (unknown origin) expressed in xenopus laevis at pH 6.9 by two electrode voltage clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Aldose reductase 2 of bovine lensMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Aldose reductase 2 of bovine lensMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+3nMAssay Description:The compound was tested for Inhibitory effect against Aldose reductase 1 in bovine kidneysMore data for this Ligand-Target Pair
Affinity DataIC50: 1.74E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of Aldose reductase 2 of bovine lensMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Aldose reductase 2 of bovine lensMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of bovine lens ALR2More data for this Ligand-Target Pair
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair