Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: <1.20nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Binding affinity to Bcl-2 (unknown origin)More data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSubstance-K receptor(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 153nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 298nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 530nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 580nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Binding affinity to Bcl-XL (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 870nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 970nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSubstance-K receptor(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 1.79E+3nMAssay Description:Binding affinity to Bak/Mcl-1 (unknown origin) protein protein interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 4.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 4.40E+3nMAssay Description:Binding affinity to human SSTR4More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 4.40E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Binding affinity to human SSTR5More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 5.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 5.40E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 6.80E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 6.90E+3nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 7.20E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 7.77E+3nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 8.20E+3nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to Bcl-2 (unknown origin) assessed as inhibition constant by fluorescence polarisation assayMore data for this Ligand-Target Pair