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Found 116 with Last Name = 'nanba' and Initial = 'e'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi:  90nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  300nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50525017(CHEMBL4462117)
Affinity DataKi:  500nMAssay Description:Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50525014(CHEMBL4475419)
Affinity DataKi:  500nMAssay Description:Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50525016(CHEMBL4457217)
Affinity DataKi:  500nMAssay Description:Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50525018(CHEMBL4465842)
Affinity DataKi:  500nMAssay Description:Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50525020(CHEMBL4518572)
Affinity DataKi:  500nMAssay Description:Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50525015(CHEMBL4435118)
Affinity DataKi:  500nMAssay Description:Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  600nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  900nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))
Affinity DataKi:  940nM ΔG°:  -35.8kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))
Affinity DataKi:  1.10E+3nM ΔG°:  -35.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))
Affinity DataKi:  1.20E+3nM ΔG°:  -35.2kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
University Of Seville

Curated by ChEMBL
LigandPNGBDBM50375511(CHEMBL406973)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using o-nitrophenyl alpha-D-galactopyranoside after 10 to 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50525019(CHEMBL4471561)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Escherichia coli (Enterobacteria))
University Of Seville

Curated by ChEMBL
LigandPNGBDBM50375511(CHEMBL406973)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of Escherichia coli beta-galactosidase using o-nitrophenyl beta-D-galactopyranoside after 10 to 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101405(CHEMBL3393931)
Affinity DataKi:  5.50E+3nMpH: 7.3Assay Description:Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50525021(CHEMBL4483772)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  7.20E+3nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  9.30E+3nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101398(CHEMBL3393930)
Affinity DataKi:  1.11E+4nMpH: 7.3Assay Description:Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101399(CHEMBL3393929)
Affinity DataKi:  1.18E+4nMpH: 7.3Assay Description:Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi:  1.19E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101401(CHEMBL3393928)
Affinity DataKi:  1.93E+4nMpH: 7.3Assay Description:Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  2.08E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101403(CHEMBL3393932)
Affinity DataKi:  2.26E+4nMpH: 7.3Assay Description:Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101402(CHEMBL3393927)
Affinity DataKi:  2.64E+4nMpH: 7.3Assay Description:Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  3.26E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  4.47E+4nM ΔG°:  -25.8kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101402(CHEMBL3393927)
Affinity DataKi:  4.50E+4nMpH: 5.5Assay Description:Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  4.90E+4nM ΔG°:  -25.6kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228802(5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...)
Affinity DataKi:  5.33E+4nM ΔG°:  -25.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101403(CHEMBL3393932)
Affinity DataKi:  6.10E+4nMpH: 5.5Assay Description:Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  6.18E+4nM ΔG°:  -25.0kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101405(CHEMBL3393931)
Affinity DataKi:  6.20E+4nMpH: 5.5Assay Description:Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101398(CHEMBL3393930)
Affinity DataKi:  6.60E+4nMpH: 5.5Assay Description:Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228802(5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...)
Affinity DataKi:  6.83E+4nM ΔG°:  -24.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228802(5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...)
Affinity DataKi:  6.88E+4nM ΔG°:  -24.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236281(CHEMBL4076141)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi:  9.00E+4nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50101401(CHEMBL3393928)
Affinity DataKi:  9.80E+4nMpH: 5.5Assay Description:Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
University Of Seville

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
University Of Seville

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of jack bean alpha-mannosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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