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Found 173 with Last Name = 'negi' and Initial = 'a'
TargetAromatase(Homo sapiens (Human))
Central Institute Of Medicinal And Aromatic Plants

LigandPNGBDBM19461(α-CA inhibitor, 5 | 5,7-dihydroxy-2-(4-hydrox...)
Affinity DataKi:  0.00110nM IC50:  1.00E+3nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central Institute Of Medicinal And Aromatic Plants

LigandPNGBDBM92556(Neoflavonoid, 8)
Affinity DataKi:  0.00182nM IC50:  1.21E+4nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central Institute Of Medicinal And Aromatic Plants

LigandPNGBDBM92555(Neoflavonoid, 7)
Affinity DataKi:  0.00216nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central Institute Of Medicinal And Aromatic Plants

LigandPNGBDBM92557(Neoflavonoid, 9)
Affinity DataKi:  0.00256nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central Institute Of Medicinal And Aromatic Plants

LigandPNGBDBM92559(Neoflavonoid, 11)
Affinity DataKi:  0.00425nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central Institute Of Medicinal And Aromatic Plants

LigandPNGBDBM92560(Neoflavonoid, 19)
Affinity DataKi:  0.00597nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central Institute Of Medicinal And Aromatic Plants

LigandPNGBDBM92558(Neoflavonoid, 10)
Affinity DataKi:  0.00838nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Central Institute Of Medicinal And Aromatic Plants

LigandPNGBDBM92561(Neoflavonoid, 20)
Affinity DataKi:  0.0118nMAssay Description:Inhibition assay using aromatase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50591659(CHEMBL5196373)
Affinity DataKi: <1.20nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50024204(1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...)
Affinity DataKi:  2.80nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50330247(6,6',7,7'-Tetrahydroxy-5,5'-diisopropyl-3,3'-dimet...)
Affinity DataKi:  35nMAssay Description:Binding affinity to Bcl-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50303503(CHEMBL4160782 | US10858316, Compound SF-5-141)
Affinity DataKi:  120nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50591668(CHEMBL5198484)
Affinity DataKi:  153nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50013858(CHEMBL3265291)
Affinity DataKi:  180nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50303352(CHEMBL4164057)
Affinity DataKi:  180nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50591660(CHEMBL3818394)
Affinity DataKi:  200nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50581328(CHEMBL5090868)
Affinity DataKi:  298nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50303139(CHEMBL4171930)
Affinity DataKi:  320nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50591661(CHEMBL5186810)
Affinity DataKi:  530nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507589(CHEMBL4586779)
Affinity DataKi:  580nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50330247(6,6',7,7'-Tetrahydroxy-5,5'-diisopropyl-3,3'-dimet...)
Affinity DataKi:  660nMAssay Description:Binding affinity to Bcl-XL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  870nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  970nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507589(CHEMBL4586779)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50051567(5-{(2R,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-[2-(1H-...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507592(CHEMBL4532486)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50266958(CHEMBL4077940)
Affinity DataKi:  1.79E+3nMAssay Description:Binding affinity to Bak/Mcl-1 (unknown origin) protein protein interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507590(CHEMBL4557933)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507592(CHEMBL4532486)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507584(CHEMBL4544582)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50303215(CHEMBL4167501)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507590(CHEMBL4557933)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507581(CHEMBL3589939)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507585(CHEMBL4549840)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507584(CHEMBL4544582)
Affinity DataKi:  3.90E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507582(CHEMBL4519358)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50333650(5-(((2R,3R,4R,5S)-1-(2-(1H-indol-3-yl)ethyl)-3,4,5...)
Affinity DataKi:  4.40E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  4.70E+3nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50333650(5-(((2R,3R,4R,5S)-1-(2-(1H-indol-3-yl)ethyl)-3,4,5...)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507594(CHEMBL4577766)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507594(CHEMBL4577766)
Affinity DataKi:  5.40E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50507583(CHEMBL4461404)
Affinity DataKi:  6.80E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in African green monkey COS1 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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