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Found 76 with Last Name = 'nemeth' and Initial = 'g'
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074439(1-(2-Bromo-4,6-dimethoxy-phenyl)-4,6-dimethyl-1H-p...)
Affinity DataKi:  1nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074411((2-Bromo-4,6-dimethoxy-phenyl)-(4,6-dimethyl-pyrim...)
Affinity DataKi:  5nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074372((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-mor...)
Affinity DataKi:  22nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074435(1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-morpholi...)
Affinity DataKi:  28nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074420(1-(2-Bromo-4,6-dimethoxy-phenyl)-4,6-dimethyl-1H-p...)
Affinity DataKi:  29nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074425(1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-phenyl-1...)
Affinity DataKi:  34nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074429(1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-phenyl-1...)
Affinity DataKi:  36nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074351((4,6-Dimethyl-pyrimidin-2-yl)-ethyl-(2-iodo-4-isop...)
Affinity DataKi:  38nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074353((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-m...)
Affinity DataKi:  43nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074350((2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimid...)
Affinity DataKi:  46nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074437(1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyr...)
Affinity DataKi:  47nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074432((4,6-Dimethyl-pyrimidin-2-yl)-(2-iodo-4-isopropyl-...)
Affinity DataKi:  48nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074430(1-(2-Bromo-4-isopropyl-phenyl)-4-chloro-6-methyl-1...)
Affinity DataKi:  67nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074419(1-(2-Bromo-4-isopropyl-phenyl)-6-chloro-4-methyl-1...)
Affinity DataKi:  79nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074408((2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimid...)
Affinity DataKi:  96nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074423(1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-4-morpholi...)
Affinity DataKi:  112nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074442(1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-1H-pyrrolo...)
Affinity DataKi:  222nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074427(1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyr...)
Affinity DataKi:  363nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074417(1-(2-Bromo-4-isopropyl-phenyl)-6-chloro-4-methyl-1...)
Affinity DataKi:  446nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074440(1-(2-Bromo-4-isopropyl-phenyl)-4-chloro-6-methyl-1...)
Affinity DataKi:  722nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074418((2-Bromo-4-isopropyl-phenyl)-(2,6-dimethyl-pyrimid...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074424(1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-1H-pyrrolo...)
Affinity DataKi:  1.28E+3nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074433(1-(4-Isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3...)
Affinity DataKi:  2.46E+3nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074421(1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyr...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074426(1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-1H-pyrrolo...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074441(1-(2-Bromo-4-isopropyl-phenyl)-4,6-dimethyl-1H-pyr...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074431(1-(2-Bromo-4-isopropyl-phenyl)-6-methyl-7-oxy-1H-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074436((2-Bromo-4-isopropyl-phenyl)-(4,6-dimethyl-pyrimid...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074438(1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-1H-pyrrolo...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074416(1-(2-Bromo-4-isopropyl-phenyl)-6-hydroxy-4-methyl-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074422(1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-6-phenyl-1...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074415(1-(2-Bromo-4-isopropyl-phenyl)-4-methyl-6-phenyl-1...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity was determined against corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29466(Pyrazolo[1,5-a]-1,3,5-triazine, 12-35)
Affinity DataIC50:  1nMT: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29452(Pyrazolo[1,5-a]-1,3,5-triazine, 12-21)
Affinity DataIC50:  1nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29468(Pyrazolo[1,5-a]-1,3,5-triazine, 12-37)
Affinity DataIC50:  1.18nMT: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29450(Pyrazolo[1,5-a]-1,3,5-triazine, 12-19)
Affinity DataIC50:  1.20nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29453(Pyrazolo[1,5-a]-1,3,5-triazine, 12-22)
Affinity DataIC50:  1.48nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29467(Pyrazolo[1,5-a]-1,3,5-triazine, 12-36)
Affinity DataIC50:  1.64nMT: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29456(Pyrazolo[1,5-a]-1,3,5-triazine, 12-25)
Affinity DataIC50:  1.72nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29457(Pyrazolo[1,5-a]-1,3,5-triazine, 12-26)
Affinity DataIC50:  1.78nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29458(Pyrazolo[1,5-a]-1,3,5-triazine, 12-27)
Affinity DataIC50:  1.80nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29440(Pyrazolo[1,5-a]-1,3,5-triazine, 12-9)
Affinity DataIC50:  1.88nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29465(Pyrazolo[1,5-a]-1,3,5-triazine, 12-34)
Affinity DataIC50:  1.90nMT: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29438(Pyrazolo[1,5-a]-1,3,5-triazine, 12-7)
Affinity DataIC50:  1.96nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29464(Pyrazolo[1,5-a]-1,3,5-triazine, 12-33)
Affinity DataIC50:  1.98nMT: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29448(Pyrazolo[1,5-a]-1,3,5-triazine, 12-17)
Affinity DataIC50:  2.14nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29439(Pyrazolo[1,5-a]-1,3,5-triazine, 12-8)
Affinity DataIC50:  2.16nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29437(Pyrazolo[1,5-a]-1,3,5-triazine, 12-6)
Affinity DataIC50:  2.30nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29460(Pyrazolo[1,5-a]-1,3,5-triazine, 12-29)
Affinity DataIC50:  2.48nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29436(Pyrazolo[1,5-a]-1,3,5-triazine, 12-5)
Affinity DataIC50:  2.58nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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