Compile Data Set for Download or QSAR
maximum 50k data
Found 685 with Last Name = 'nepali' and Initial = 'k'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50546246(CHEMBL4753043 | US11608319, Compound AR-13503)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human ROCK1 expressed in baculovirus expression system by Kinase-Glo luminescent AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50546246(CHEMBL4753043 | US11608319, Compound AR-13503)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human ROCK2 expressed in baculovirus expression system by Kinase-Glo luminescent AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM108255(US8609833, 86)
Affinity DataKi:  0.970nMAssay Description:Binding affinity to A1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50118812((2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylami...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to A3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50598611(CHEMBL5187502)
Affinity DataKi:  4nMAssay Description:Binding affinity to TSPO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50546247(AR-11324 FREE BASE | AR-13324 | Netarsudil | US114...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of human ROCK2 by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50245492(CHEMBL4082554)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using pro-TNFalpha peptide Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505036(CHEMBL4540138)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505037(CHEMBL4473277)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505038(CHEMBL4516232)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505039(CHEMBL4439982)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505035(CHEMBL4527121)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505040(CHEMBL4560430)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247556(CHEMBL4104117)
Affinity DataIC50:  0.291nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50236621(CHEMBL4078142)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using pro-TNFalpha peptide Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of human full length recombinant MAO-A expressed in insect cells using kynuramine as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50245498(CHEMBL4083562)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of recombinant human ASK1 using STK3 peptide as substrate incubated for 30 mins followed by ATP addition measured for 3 hrs by TR-FRET ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Sus scrofa)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50235214(CHEMBL4084903)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of porcine cholesterol esterase using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247553(CHEMBL4095667)
Affinity DataIC50:  0.795nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50613597(CHEMBL5270626)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613596(CHEMBL5272356)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613595(CHEMBL5272100)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613594(CHEMBL5275755)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613593(CHEMBL5285324)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of HDAC6 (unknown origin) by colorimetric methodMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Sus scrofa)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50235213(CHEMBL4102852)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of porcine cholesterol esterase using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Sus scrofa)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50235212(CHEMBL4092661)
Affinity DataIC50:  2nMAssay Description:Inhibition of porcine cholesterol esterase using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50551233(CHEMBL4790152)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac)-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of HDAC1 (unknown origin) by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247580(CHEMBL4091237)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247560(CHEMBL4063376)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50305548(1-(4-(4-(3,6-dihydro-2H-pyran-4-yl)-1-(2,2,2-trifl...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac)-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247582(CHEMBL4098833)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Sus scrofa)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50159614(2-(2-Fluoro-phenyl)-benzo[h]chromen-4-one | CHEMBL...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of porcine cholesterol esterase using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247570(CHEMBL4079874)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247561(CHEMBL4085971)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human HDAC6 using RHKKAc as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247592(CHEMBL4101436)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50546248(CHEMBL3185765)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of ROCK2 (unknown origin) using histone as substrate incubated for 20 mins in presence of [gamma32P]-ATP by liquid scintillation counter m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HDAC3 (unknown origin) by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247579(CHEMBL4073165)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus infected insect cells using [RHKK(Ac)] fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in Sf9 cells using FTS as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247571(CHEMBL4068310)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)
Affinity DataIC50:  5nMAssay Description:Inhibition of human CDK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50613599(CHEMBL5273296)
Affinity DataIC50:  5nMAssay Description:Inhibition of SYK (unknown origin) using biotinylated EDPDYEWPSA as substrate incubated for 30 mins in presence of 33P-ATP by Scintillation Proximity...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50613600(CHEMBL5285207)
Affinity DataIC50:  5nMAssay Description:Inhibition of SYK (unknown origin) using biotinylated EDPDYEWPSA as substrate incubated for 30 mins in presence of 33P-ATP by Scintillation Proximity...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Displayed 1 to 50 (of 685 total ) | Next | Last >>
Jump to: