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Found 169 with Last Name = 'neubert' and Initial = 'ad'
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036427(CHEMBL350265 | [3,5-Dibromo-4-(4-hydroxy-3-isoprop...)
Affinity DataIC50:  0.100nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036401(CHEMBL163221 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  0.100nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.110nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036399(Axitirome | CHEMBL159682 | N-(4-{3-[(4-Fluoro-phen...)
Affinity DataIC50:  0.140nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)
Affinity DataIC50:  0.150nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036402(CHEMBL46882 | N-[3,5-dimethyl-4-(4'-hydroxy-3'-iso...)
Affinity DataIC50:  0.190nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036418(CHEMBL350049 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  0.230nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036423(CHEMBL164421 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  0.260nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036411(CHEMBL163324 | N-{3,5-Dichloro-4-[3-(4-chloro-benz...)
Affinity DataIC50:  0.270nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036410(CHEMBL159976 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)
Affinity DataIC50:  0.310nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036424(CHEMBL159334 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)
Affinity DataIC50:  0.370nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036408(CHEMBL161828 | N-{4-[3-(4-Chloro-benzyl)-4-hydroxy...)
Affinity DataIC50:  0.430nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036417(CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)
Affinity DataIC50:  0.680nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036417(CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)
Affinity DataIC50:  0.680nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036404(CHEMBL159595 | N-(4-{3-[(4-Fluoro-phenyl)-hydroxy-...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036395(CHEMBL350199 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  0.950nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036420(CHEMBL161535 | N-[4-(3-Isopropyl-4-methoxy-phenoxy...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064106(CGS-26303 | CHEMBL290698 | {[(R)-2-Biphenyl-4-yl-1...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036397(CHEMBL348983 | N-[3,5-Dichloro-4-(4-hydroxy-3-isop...)
Affinity DataIC50:  1.10nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036406(CHEMBL163380 | [3,5-Dichloro-4-(4-hydroxy-3-isopro...)
Affinity DataIC50:  1.10nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036398(CHEMBL162692 | [3,5-Dibromo-4-(4-hydroxy-3-isoprop...)
Affinity DataIC50:  1.5nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036405(CHEMBL434476 | N-(3,5-Dichloro-4-{3-[(4-chloro-phe...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036426(CHEMBL159610 | N-{4-[3-(4-Fluoro-benzoyl)-4-hydrox...)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036415(CHEMBL163268 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036414(CHEMBL346112 | N-{4-[3-(4-Chloro-benzoyl)-4-hydrox...)
Affinity DataIC50:  3.30nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036430(CHEMBL347713 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)
Affinity DataIC50:  3.5nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036422(CHEMBL163020 | N-[3,5-Difluoro-4-(4-hydroxy-3-isop...)
Affinity DataIC50:  3.60nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  4.40nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036409((S)-2-Amino-3-[3,5-dibromo-4-(4-hydroxy-3-isopropy...)
Affinity DataIC50:  4.5nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064109(CGS-31447 | CHEMBL285619 | {1-[(S)-2-Biphenyl-4-yl...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036396(CHEMBL163320 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036432(CHEMBL264041 | N-[4-(3-Isopropyl-phenoxy)-3,5-dime...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239481(CHEMBL4061308)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036403(CHEMBL352126 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)
Affinity DataIC50:  12nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064114((S)-3-Biphenyl-4-yl-2-[(S)-5-(2-fluoro-phenyl)-2-(...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064125((S)-3-Cyclohexyl-2-[(S)-5-(2,4-difluoro-phenyl)-2-...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064096(CHEMBL40028 | {[(S)-4-(2-Fluoro-phenyl)-1-(2H-tetr...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036412(CHEMBL161245 | N-[4-(3-Isopropyl-4-methoxy-phenoxy...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239482(CHEMBL1683001)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064109(CGS-31447 | CHEMBL285619 | {1-[(S)-2-Biphenyl-4-yl...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239480(CHEMBL4074410)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036407(CHEMBL441101 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239484(CHEMBL4103025)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064124((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064113(CHEMBL40168 | {[(S)-1-(2-Biphenyl-4-yl-ethylcarbam...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064112((S)-5-(2-Fluoro-phenyl)-2-[(S)-5-(2-fluoro-phenyl)...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50388921(CHEMBL2063281)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant His6-tagged DGAT1 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50388923(CHEMBL2063283)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant His6-tagged DGAT1 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239483(CHEMBL4088335)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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