Found 1476 with Last Name = 'ng' and Initial = 'py' 
Affinity DataKi: 1.40nMAssay Description:Inhibition of human full-length recombinant PARP-1More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 1.60nMAssay Description:Competitive inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using Boc-Lys (Ac)-AMC as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using Boc-Lys (Ac)-AMC as substrate preincubated...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of human HDAC6 CD2 expressed in Escherichia coli BL21 (RIL) using Boc-Lys (Ac)-AMC as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using Boc-Lys (Ac)-AMC as substrate preincubated...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Competitive inhibition of human HDAC6 CD2 expressed in Escherichia coli BL21 (RIL) using Boc-Lys (Ac)-AMC as substrate preincubated for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using Boc-Lys (Ac)-AMC as substrate preincubated...More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of human HDAC6 CD2 expressed in Escherichia coli BL21 (RIL) using Boc-Lys (Ac)-AMC as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 1.32E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor in calf caudate homogenates.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 1.91E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptor in rat cortex homogenates.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 2.19E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptor in rat cortex homogenates.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 3.80E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor in calf caudate homogenates.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 5.50E+3nMAssay Description:Affinity pKi for 5-hydroxytryptamine 2C receptor was measured in rat cortex homogenates.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataKi: 5.62E+3nMAssay Description:Affinity pKi for Alpha-2 adrenergic receptor was measured in rat cortex homogenates.More data for this Ligand-Target Pair
Affinity DataKi: 7.94E+3nMAssay Description:Affinity pKi for 5-hydroxytryptamine 2A receptor was measured in rat cortex homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 9.33E+3nMAssay Description:Affinity pKi for 5-hydroxytryptamine 1A receptor was measured in rat cortex homogenates.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Affinity pKi for 5-hydroxytryptamine 1D receptor was measured in calf caudate homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 1.07E+4nMAssay Description:Affinity pKi for Dopamine receptor D2 was measured in rat cortex homogenatesMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataKi: 1.12E+4nMAssay Description:Affinity pKi for Alpha-1 adrenergic receptor was measured in rat cortex homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 1.48E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in rat cortex homogenates.More data for this Ligand-Target Pair
Affinity DataKi: 3.24E+4nMAssay Description:Affinity pKi for Dopamine receptor D1 was measured in rat cortex homogenates.More data for this Ligand-Target Pair
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataKi: 4.57E+4nMAssay Description:Affinity pKi for Beta adrenergic receptor was measured in rat cortex homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 6.76E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in rat cortex homogenates.More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of PARP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human recombinant PARP-1 (662 to 1011 residues)More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of PARP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PARP-1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mouse recombinant PARP-2More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PARP-1 using histone as substrate incubated for 16 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PARP-2 using histone as substrate incubated for 16 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human HDAC6 using fluorescent-labeled peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate af...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length recombinant human HDAC6 using fluorescent-labeled peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of PARP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate af...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of SCD1 in mouse liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of PARP-2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
