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Found 195 with Last Name = 'nonato' and Initial = 'mc'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant DHODH expressed in baculovirus infected insect cells using dihydroorotate as substrate in presence of quinone by dich...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523223(CHEMBL4540838)
Affinity DataIC50:  19nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50384788(LAPACHOL)
Affinity DataIC50:  19nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523217(CHEMBL155771)
Affinity DataIC50:  23nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523213(CHEMBL4452960)
Affinity DataIC50:  78nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50384788(LAPACHOL)
Affinity DataIC50:  100nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523227(CHEMBL4472078)
Affinity DataIC50:  108nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523227(CHEMBL4472078)
Affinity DataIC50:  111nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523223(CHEMBL4540838)
Affinity DataIC50:  123nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523232(CHEMBL4457147)
Affinity DataIC50:  129nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523214(CHEMBL4560384)
Affinity DataIC50:  185nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523224(CHEMBL4474026)
Affinity DataIC50:  227nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  312nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523230(CHEMBL4566973)
Affinity DataIC50:  330nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523225(CHEMBL4527976)
Affinity DataIC50:  375nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201619(CHEMBL1237007)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50385716(CHEMBL2043303)
Affinity DataIC50:  420nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50203188(2-((1r,4r)-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy...)
Affinity DataIC50:  432nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523215(CHEMBL4586212)
Affinity DataIC50:  436nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201622(CHEMBL3914938)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523214(CHEMBL4560384)
Affinity DataIC50:  541nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201636(CHEMBL3184132)
Affinity DataIC50:  560nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523217(CHEMBL155771)
Affinity DataIC50:  709nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523228(CHEMBL2041119)
Affinity DataIC50:  711nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523213(CHEMBL4452960)
Affinity DataIC50:  808nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201627(CHEMBL3184096)
Affinity DataIC50:  910nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523232(CHEMBL4457147)
Affinity DataIC50:  911nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523230(CHEMBL4566973)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523221(CHEMBL4546952)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523229(CHEMBL62718)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201620(CHEMBL3186954)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201628(CHEMBL3188954)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523215(CHEMBL4586212)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201626(CHEMBL3184332)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523221(CHEMBL4546952)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523218(CHEMBL2408377)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523212(CHEMBL4436314)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523218(CHEMBL2408377)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201615(CHEMBL3188811)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50203188(2-((1r,4r)-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201610(CHEMBL3916793)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201617(CHEMBL3187986)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523222(CHEMBL4524841)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523224(CHEMBL4474026)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523219(CHEMBL2408378)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523222(CHEMBL4524841)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50523228(CHEMBL2041119)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL
LigandPNGBDBM50201621(CHEMBL3186409)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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