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Found 244 with Last Name = 'omori' and Initial = 'k'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035609(CHEMBL3338455)
Affinity DataIC50:  0.0530nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035620(CHEMBL3338445)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50065697(CHEMBL3404016)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP incubated for 30 mins by scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50100673(CHEMBL538498 | methyl 2-(4-aminophenyl)-4-(4-bromo...)
Affinity DataIC50:  0.220nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130021(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyridin-2...)
Affinity DataIC50:  0.220nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130017(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyrimidin...)
Affinity DataIC50:  0.230nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130025(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyrazin-2...)
Affinity DataIC50:  0.290nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130020(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyridin-2...)
Affinity DataIC50:  0.310nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130027(8-Oxo-2-(pyridin-2-ylmethoxy)-7-pyridin-4-ylmethyl...)
Affinity DataIC50:  0.380nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035617(CHEMBL3338448)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50100674(CHEMBL541818 | methyl 2-(4-aminophenyl)-4-(3,5-dim...)
Affinity DataIC50:  0.390nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130028(7-(4-Amino-phenyl)-8-oxo-2-(pyridin-2-ylmethoxy)-5...)
Affinity DataIC50:  0.510nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130024(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(2-pyridin...)
Affinity DataIC50:  0.520nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035621(CHEMBL3338444)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035613(CHEMBL3338452)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50065689(CHEMBL3404009)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP incubated for 30 mins by scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50036633(CHEMBL3354285)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50065686(CHEMBL3404006)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP incubated for 30 mins by scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50100662(CHEMBL553371 | CHEMBL77971 | methyl 2-(4-aminophen...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50100662(CHEMBL553371 | CHEMBL77971 | methyl 2-(4-aminophen...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50100662(CHEMBL553371 | CHEMBL77971 | methyl 2-(4-aminophen...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50100659(CHEMBL544289 | methyl 2-(4-aminophenyl)-1-oxo-7-(3...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50100656(2-(4-Amino-phenyl)-7-benzyloxy-1-oxo-4-(3,4,5-trim...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130029(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(2-pyridin...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50036625(CHEMBL3354279)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035618(CHEMBL3338447)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035611(CHEMBL3338453)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50065688(CHEMBL3404008)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP incubated for 30 mins by scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035615(CHEMBL3338450)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50036632(CHEMBL3354284)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035610(CHEMBL3338454)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50366818(CHEMBL1202833)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130026(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyrimidin...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035652(CHEMBL3338443)
Affinity DataIC50:  2nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50036610(CHEMBL3354264)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130019(8-Oxo-2-(pyridin-2-ylmethoxy)-7-pyridin-3-ylmethyl...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50130016(8-(2-Hydroxy-ethylamino)-2-(2-methyl-pyridin-4-ylm...)
Affinity DataIC50:  2.60nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50036612(CHEMBL3354266)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035614(CHEMBL3338451)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50065691(CHEMBL3404011)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP incubated for 30 mins by scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50100670(CHEMBL553786 | methyl 2-(4-aminophenyl)-1-oxo-7-(4...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50065690(CHEMBL3404010)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP incubated for 30 mins by scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035616(CHEMBL3338449)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50036619(CHEMBL3354273)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50035653(CHEMBL3338442)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50036611(CHEMBL3354265)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50130020(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyridin-2...)
Affinity DataIC50:  4.40nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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