Affinity DataKi: 1.30nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of estrogen receptor alphaMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of binding to recombinant human ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:Inhibition of estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Binding potency for human ER alphaMore data for this Ligand-Target Pair