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Found 144 with Last Name = 'paluchowska' and Initial = 'mh'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29563(1-(m-trifluorophenyl)piperazine, 10)
Affinity DataKi:  0.300nM ΔG°:  -56.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  0.550nMAssay Description:Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29567(1-(m-trifluorophenyl)piperazine, 14)
Affinity DataKi:  1.30nM ΔG°:  -52.8kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29565(1-(m-trifluorophenyl)piperazine, 12)
Affinity DataKi:  1.5nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29566(1-(m-trifluorophenyl)piperazine, 13)
Affinity DataKi:  2.20nM ΔG°:  -51.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29561(1-(m-trifluorophenyl)piperazine, 8)
Affinity DataKi:  2.60nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29560(1-(m-trifluorophenyl)piperazine, 7)
Affinity DataKi:  3nM ΔG°:  -50.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50357975(CHEMBL1917341)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50039787(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  4nMAssay Description:Tested in vitro for receptor binding affinity against 5-hydroxytryptamine 1A receptor using radioligand [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29563(1-(m-trifluorophenyl)piperazine, 10)
Affinity DataKi:  4nMAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50083044((3aS,7aR)-2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-y...)
Affinity DataKi:  4nMAssay Description:Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29558(1-(m-trifluorophenyl)piperazine, 5)
Affinity DataKi:  4nM ΔG°:  -49.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29557(1-(m-trifluorophenyl)piperazine, 4)
Affinity DataKi:  4nM ΔG°:  -49.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29562(1-(m-trifluorophenyl)piperazine, 9)
Affinity DataKi:  5.90nM ΔG°:  -48.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50083042(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-cyclohe...)
Affinity DataKi:  8nMAssay Description:Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29559(1-(m-trifluorophenyl)piperazine, 6)
Affinity DataKi:  9nM ΔG°:  -47.8kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50357988(CHEMBL1917354)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357993(CHEMBL1917359)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50039784(1-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataKi:  15nMAssay Description:Tested in vitro for receptor binding affinity against 5-hydroxytryptamine 1A receptor using radioligand [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50039784(1-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataKi:  15nMAssay Description:Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50039790(1-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  17nMAssay Description:Tested in vitro for receptor binding affinity against 5-hydroxytryptamine 1A receptor using radioligand [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50357976(CHEMBL1917342)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50154711(CHEMBL364124 | N-Ethyl-N-{3-[4-(2-methoxy-phenyl)-...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29556(1-(m-trifluorophenyl)piperazine, 3)
Affinity DataKi:  21nM ΔG°:  -45.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM29560(1-(m-trifluorophenyl)piperazine, 7)
Affinity DataKi:  21nM ΔG°:  -45.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50357990(CHEMBL1917356)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50039785(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataKi:  24nMAssay Description:Tested in vitro for receptor binding affinity against 5-hydroxytryptamine 1A receptor using radioligand [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29567(1-(m-trifluorophenyl)piperazine, 14)
Affinity DataKi:  24nMAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50357989(CHEMBL1917355)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357989(CHEMBL1917355)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29562(1-(m-trifluorophenyl)piperazine, 9)
Affinity DataKi:  30nMAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50357991(CHEMBL1917357)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM29564(1-(m-trifluorophenyl)piperazine, 11)
Affinity DataKi:  31nM ΔG°:  -44.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357994(CHEMBL1917360)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50083040(2-[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-cyclohexyl]...)
Affinity DataKi:  34nMAssay Description:Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29564(1-(m-trifluorophenyl)piperazine, 11)
Affinity DataKi:  34nM ΔG°:  -44.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50357978(CHEMBL1917344)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357991(CHEMBL1917357)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357988(CHEMBL1917354)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50357977(CHEMBL1917343)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50039786(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  41nMAssay Description:Tested in vitro for receptor binding affinity against 5-hydroxytryptamine 1A receptor using radioligand [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357990(CHEMBL1917356)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50039789(1-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  42nMAssay Description:Tested in vitro for receptor binding affinity against 5-hydroxytryptamine 1A receptor using radioligand [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29565(1-(m-trifluorophenyl)piperazine, 12)
Affinity DataKi:  43nMAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM29558(1-(m-trifluorophenyl)piperazine, 5)
Affinity DataKi:  46nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50083045(1-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-cyclohe...)
Affinity DataKi:  47nMAssay Description:Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM29566(1-(m-trifluorophenyl)piperazine, 13)
Affinity DataKi:  48nMAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy of Sciences

LigandPNGBDBM50083043((3aS,7aR)-2-[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-b...)
Affinity DataKi:  50nMAssay Description:Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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