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Found 73 with Last Name = 'peet' and Initial = 'c'
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259611(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)
Affinity DataKi:  7.94nMAssay Description:Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259611(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)
Affinity DataKi:  10nMAssay Description:Inhibition of TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259613(CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...)
Affinity DataKi:  25.1nMAssay Description:Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259612(CHEMBL513491 | sodium 6-(5-chloro-2-(2-chloro-4-fl...)
Affinity DataKi:  100nMAssay Description:Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414022(CHEMBL2110364 | GSK-180100B)
Affinity DataIC50:  0.129nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50:  2.51nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121279(2-Amino-1-[2-(5-ethyl-1H-imidazol-2-yl)-2,3-dihydr...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121284(2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121282((S)-1-((S)-2-aminobutanoyl)-N-butylindoline-2-carb...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259613(CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50197899(5-(2-(2-(benzyloxy)-5-(trifluoromethyl)phenyl)cycl...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259612(CHEMBL513491 | sodium 6-(5-chloro-2-(2-chloro-4-fl...)
Affinity DataIC50:  12.6nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259611(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)
Affinity DataIC50:  12.6nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)
Affinity DataIC50:  15.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121280(2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414026(CHEMBL466101)
Affinity DataIC50:  25.1nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414032(CHEMBL511252)
Affinity DataIC50:  31.6nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121283(2-Amino-1-[2-(1H-imidazol-2-yl)-2,3-dihydro-indol-...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414030(CHEMBL257998)
Affinity DataIC50:  39.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414029(CHEMBL467113)
Affinity DataIC50:  39.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414028(CHEMBL466103)
Affinity DataIC50:  39.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414027(CHEMBL466102)
Affinity DataIC50:  79.4nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414024(CHEMBL508276)
Affinity DataIC50:  79.4nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414025(CHEMBL511733)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414031(CHEMBL468723)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414023(CHEMBL258041)
Affinity DataIC50:  158nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414033(CHEMBL511919)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177043(CHEMBL3814671)
Affinity DataIC50:  339nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177042(CHEMBL3730906)
Affinity DataIC50:  427nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259611(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259611(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of EP3 receptor by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259611(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50177033(CHEMBL3813839)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177041(CHEMBL3814491)
Affinity DataIC50:  2.46E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50429613(CHEMBL2334590)
Affinity DataIC50:  2.57E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177040(CHEMBL3814642)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177039(CHEMBL3814308)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259613(CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177038(CHEMBL3814655)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50177032(CHEMBL3814407)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50177031(CHEMBL3814969)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50177044(CHEMBL3814695)
Affinity DataIC50:  6.17E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177037(CHEMBL3814438)
Affinity DataIC50:  6.46E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50177045(CHEMBL3814733)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177036(CHEMBL1528007)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259611(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177035(CHEMBL3814774)
Affinity DataIC50:  8.13E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177034(CHEMBL3813732)
Affinity DataIC50:  8.51E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121278(3-Ethyl-2,3,10,10a-tetrahydro-pyrazino[1,2-a]indol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50259611(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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