TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assayMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PDBu form PKCalphaMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]PDBu form PKCalphaMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assayMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assayMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 118nMAssay Description:Displacement of [3H]PDBu form PKCalphaMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 188nMAssay Description:Displacement of [3H]PDBu form PKCalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:The compound was tested for the concentration to inhibit 50% of tubulin polymerization.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:The compound was tested for the concentration to inhibit 50% of tubulin polymerization.More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of tubulin polymerization reported as IC50More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of tubulin polymerization reported as IC50More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of tubulin polymerization reported as IC50More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of tubulin polymerization reported as IC50More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:The compound was tested for the concentration to inhibit 50% of tubulin polymerization.More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Compound was tested for its ability to inhibit the glutamate induced polymerization of tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:The compound was tested for the concentration to inhibit 50% of tubulin polymerization.More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of tubulin polymerization reported as IC50More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization reported as IC50More data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: >8.00E+4nMAssay Description:The compound was tested for the concentration to inhibit 50% of tubulin polymerization.More data for this Ligand-Target Pair