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Found 558 with Last Name = 'pi?lar' and Initial = 'a'
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50247011(CHEMBL4080419)
Affinity DataKi:  0.0110nMAssay Description:Competitive inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate at pH 8 by stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50247011(CHEMBL4080419)
Affinity DataKi:  0.0110nMAssay Description:Competitive inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate at pH 8 by stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataKi:  0.163nMAssay Description:Competitive inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate at pH 8 by stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50468733(CHEMBL4294570)
Affinity DataKi:  1.10nMAssay Description:Competitive inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50468736(CHEMBL4283585)
Affinity DataKi:  1.70nMAssay Description:Competitive inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50027375(CHEMBL3338394)
Affinity DataKi:  2.70nMAssay Description:Inhibition of recombinant human BChE at 50 nM by stopped flow apparatus methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50556656(CHEMBL4759301)
Affinity DataKi:  25nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using varying level of p-tyramine as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50027377(CHEMBL3338395)
Affinity DataKi:  27nMAssay Description:Inhibition of recombinant human BChE at 50 nM by stopped flow apparatus methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50556660(CHEMBL4758739)
Affinity DataKi:  34nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using varying level of p-tyramine as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataKi:  40nMAssay Description:Reversible inhibition of recombinant human MAOA expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins by...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50556664(CHEMBL4746352)
Affinity DataKi:  77nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using varying level of p-tyramine as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50556671(CHEMBL4757484)
Affinity DataKi:  107nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using varying level of p-tyramine as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataKi:  220nMAssay Description:Irreversible inhibition of recombinant human MAOA expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50506401(CHEMBL4450588)
Affinity DataKi:  230nMAssay Description:Reversible inhibition of recombinant human MAOA expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataKi:  970nMAssay Description:Reversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50506401(CHEMBL4450588)
Affinity DataKi:  1.01E+3nMAssay Description:Irreversible inhibition of recombinant human MAOA expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506400(CHEMBL4458212)
Affinity DataKi:  1.25E+3nMAssay Description:Reversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506402(CHEMBL4558431)
Affinity DataKi:  1.36E+3nMAssay Description:Reversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506394(CHEMBL4576799)
Affinity DataKi:  1.38E+3nMAssay Description:Irreversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506394(CHEMBL4576799)
Affinity DataKi:  1.92E+3nMAssay Description:Reversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataKi:  5.68E+3nMAssay Description:Irreversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506402(CHEMBL4558431)
Affinity DataKi:  6.55E+3nMAssay Description:Irreversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506400(CHEMBL4458212)
Affinity DataKi:  1.73E+4nMAssay Description:Irreversible inhibition of recombinant human MAOB expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50247022(CHEMBL4089230)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 300 secs followed by substrate addition measured f...More data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  2nMAssay Description:Inhibition of equine serum BuChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant human microsomal MAOA expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect cells using p-tyramine as substrate preincubated for 15 min...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine as substrate preincubated for 300 secs followed by substrate addition and measured for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50246979(CHEMBL4105611 | US20230331674, Table 1.1)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 300 secs followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAcetylcholinesterase(Mus musculus (mouse))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of AChE in mouse brain homogenate using acetylthiocholine as substrate preincubated for 300 secs followed by substrate addition by Ellman'...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506402(CHEMBL4558431)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50468744(CHEMBL4280947)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured for 1 min b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Electrophorus electricus AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50468733(CHEMBL4294570)
Affinity DataIC50:  11nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured for 1 min b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506417(CHEMBL4465204)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human BChE by Ellman methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50027375(CHEMBL3338394)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human BChE by Ellman methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50468736(CHEMBL4283585)
Affinity DataIC50:  14nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured for 1 min b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50247010(CHEMBL4068039)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 300 secs followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506400(CHEMBL4458212)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50468741(CHEMBL4291165)
Affinity DataIC50:  19nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured for 1 min b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50027376(CHEMBL3338391)
Affinity DataIC50:  21nMAssay Description:Inhibition of human BuCheMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50027376(CHEMBL3338391)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human BChE by Ellman methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours

Curated by ChEMBL
LigandPNGBDBM50506396(CHEMBL4544548)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50027376(CHEMBL3338391)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 300 secs followed by substrate addition measured f...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  22nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant BuChe using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured for 1 min...More data for this Ligand-Target Pair
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