TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <0.100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <1nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...More data for this Ligand-Target Pair