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Found 16 with Last Name = 'polishook' and Initial = 'jd'
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292415(CHEMBL504845 | Zaragozic Acid B)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292333(CHEMBL505374 | zaragozic acid C)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292413(CHEMBL502210 | Zaragozic Acid D2)
Affinity DataIC50:  2nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50292414(CHEMBL502872 | Zaragozic Acid D)
Affinity DataIC50:  6nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50242053(6,8-didec-(1Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-in...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071242(Acetic acid (6aR,6bS,9S,10aR,12aS)-5-hydroxy-1,3-d...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071241(Acetic acid (6aR,6bS,9S,10aR,12aS)-5-hydroxy-6b,10...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478534(Australifungin | CHEBI:65459)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50242056(CHEMBL469856 | fuscinarin)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of MIP1alpha binding to human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478533(CHEBI:65719 | Cytosporic Acid)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50242054(CHEMBL469855 | ophiobolin C)
Affinity DataIC50:  4.00E+4nMAssay Description:Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478406(Integrasone)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50242055(19,20-epoxycytochalasin Q | CHEMBL449278)
Affinity DataIC50:  6.00E+4nMAssay Description:Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071240(Acetic acid (3S,4aR,6aS,12aR,12bS)-11-hydroxy-8,9-...)
Affinity DataIC50:  4.60E+5nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071239(Acetic acid (3S,4aR,6aS,12aR,12bS)-8,9-diformyl-11...)
Affinity DataIC50:  5.60E+5nMAssay Description:Inhibition of human recombinant farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed