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Found 28 with Last Name = 'polzer' and Initial = 'h'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551643(CHEMBL4790597)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551643(CHEMBL4790597)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551649(CHEMBL4765060)
Affinity DataIC50:  3nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551649(CHEMBL4765060)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551647(CHEMBL4755980)
Affinity DataIC50:  11nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551650(CHEMBL4754982)
Affinity DataIC50:  12nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551650(CHEMBL4754982)
Affinity DataIC50:  28nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551648(CHEMBL4740264)
Affinity DataIC50:  34nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551646(CHEMBL4751666)
Affinity DataIC50:  85nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551645(CHEMBL4764595)
Affinity DataIC50:  133nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataIC50:  137nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551647(CHEMBL4755980)
Affinity DataIC50:  240nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551646(CHEMBL4751666)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551648(CHEMBL4740264)
Affinity DataIC50:  2.08E+3nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551645(CHEMBL4764595)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  2.49E+3nMAssay Description:Inhibition of human DDR2 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  3.26E+3nMAssay Description:Inhibition of human ZAK incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  3.86E+3nMAssay Description:Inhibition of human MAP4K4 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 7(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  3.26E+3nMAssay Description:Inhibition of human EPHA7 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  2.49E+3nMAssay Description:Inhibition of human RET incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd:  340nMAssay Description:Binding affinity to human partial length FLT3 ITD/F691L double mutant expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataKd:  115nMAssay Description:Binding affinity to human partial length FLT3 ITD/F691L double mutant expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 16(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  1.77E+3nMAssay Description:Inhibition of human CDK16 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  3.86E+3nMAssay Description:Inhibition of human NTRK1 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  1.77E+3nMAssay Description:Inhibition of human FLT3 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed