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Found 321 with Last Name = 'pontén' and Initial = 'f'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108452(3-(5-Chloro-2-methoxy-phenyl)-1-(1-phenyl-2-pyrrol...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM21130(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards Opioid receptor kappa 1 by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108437(3-(3-Nitro-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-e...)
Affinity DataIC50:  2.20nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108436(3-(3,4-Dichloro-phenyl)-1-(1-phenyl-2-pyrrolidin-1...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195239(CHEMBL3972563 | US10287258, Example 29 | US1066924...)
Affinity DataIC50:  2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195239(CHEMBL3972563 | US10287258, Example 29 | US1066924...)
Affinity DataIC50:  2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195239(CHEMBL3972563 | US10287258, Example 29 | US1066924...)
Affinity DataIC50:  2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195239(CHEMBL3972563 | US10287258, Example 29 | US1066924...)
Affinity DataIC50:  2.40nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM604873((2S)-N-[(1S)-1-Cyano-2-[4-(3-methyl-2-oxo-2,3-dihy...)
Affinity DataIC50:  2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108450(3-(3-Chloro-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195239(CHEMBL3972563 | US10287258, Example 29 | US1066924...)
Affinity DataIC50:  2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195239(CHEMBL3972563 | US10287258, Example 29 | US1066924...)
Affinity DataIC50:  2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385058((2S)-N-[(1S)-1-Cyano-2-{4-[3-(2-methoxyethyl)-2-ox...)
Affinity DataIC50:  3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385058((2S)-N-[(1S)-1-Cyano-2-{4-[3-(2-methoxyethyl)-2-ox...)
Affinity DataIC50:  3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385058((2S)-N-[(1S)-1-Cyano-2-{4-[3-(2-methoxyethyl)-2-ox...)
Affinity DataIC50:  3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385058((2S)-N-[(1S)-1-Cyano-2-{4-[3-(2-methoxyethyl)-2-ox...)
Affinity DataIC50:  3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385058((2S)-N-[(1S)-1-Cyano-2-{4-[3-(2-methoxyethyl)-2-ox...)
Affinity DataIC50:  3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385058((2S)-N-[(1S)-1-Cyano-2-{4-[3-(2-methoxyethyl)-2-ox...)
Affinity DataIC50:  3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385058((2S)-N-[(1S)-1-Cyano-2-{4-[3-(2-methoxyethyl)-2-ox...)
Affinity DataIC50:  3.16nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108447(3-(5-Fluoro-2-methoxy-phenyl)-1-(1-phenyl-2-pyrrol...)
Affinity DataIC50:  3.40nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108432(3-(2,5-Dimethoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-...)
Affinity DataIC50:  3.40nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50:  4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50:  4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50:  4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50:  4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50:  4.47nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50:  4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50:  4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:Examples 36-37: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385055((2S)-N-{(1S)-1-Cyano-2-[4-(7-fluoro-3-methyl-2-oxo...)
Affinity DataIC50:  5.13nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385055((2S)-N-{(1S)-1-Cyano-2-[4-(7-fluoro-3-methyl-2-oxo...)
Affinity DataIC50:  5.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385055((2S)-N-{(1S)-1-Cyano-2-[4-(7-fluoro-3-methyl-2-oxo...)
Affinity DataIC50:  5.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385055((2S)-N-{(1S)-1-Cyano-2-[4-(7-fluoro-3-methyl-2-oxo...)
Affinity DataIC50:  5.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385055((2S)-N-{(1S)-1-Cyano-2-[4-(7-fluoro-3-methyl-2-oxo...)
Affinity DataIC50:  5.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385055((2S)-N-{(1S)-1-Cyano-2-[4-(7-fluoro-3-methyl-2-oxo...)
Affinity DataIC50:  5.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385055((2S)-N-{(1S)-1-Cyano-2-[4-(7-fluoro-3-methyl-2-oxo...)
Affinity DataIC50:  5.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385077(BDBM445985 | US10287258, Example 37 | US11667615, ...)
Affinity DataIC50:  5.25nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385077(BDBM445985 | US10287258, Example 37 | US11667615, ...)
Affinity DataIC50:  5.25nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385077(BDBM445985 | US10287258, Example 37 | US11667615, ...)
Affinity DataIC50:  5.25nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385077(BDBM445985 | US10287258, Example 37 | US11667615, ...)
Affinity DataIC50:  5.25nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385077(BDBM445985 | US10287258, Example 37 | US11667615, ...)
Affinity DataIC50:  5.25nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385077(BDBM445985 | US10287258, Example 37 | US11667615, ...)
Affinity DataIC50:  5.25nMAssay Description:Examples 36-37: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385077(BDBM445985 | US10287258, Example 37 | US11667615, ...)
Affinity DataIC50:  5.25nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108434(3-[2-Oxo-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1,2-...)
Affinity DataIC50:  5.30nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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